From the Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.
Clin Nucl Med. 2022 Nov 1;47(11):e710-e712. doi: 10.1097/RLU.0000000000004355. Epub 2022 Aug 16.
Neurofibromatosis type 2 (NF2) is an autosomal-dominant tumor predisposing syndrome that results from mutations in the NF2 tumor suppressor gene on chromosome 22. The development of bilateral vestibular schwannomas is the characteristic feature of the disease. However, other nervous system tumors, including meningiomas, ependymomas, and schwannomas, can be seen frequently. Herein, we present 68 Ga-DOTATATE PET/CT findings of 2 siblings with NF2.
神经纤维瘤病 2 型（NF2）是一种常染色体显性遗传的肿瘤易感性综合征，由 22 号染色体上的 NF2 肿瘤抑制基因的突变引起。双侧前庭神经鞘瘤的发生是该疾病的特征性表现。然而，也可以经常见到其他神经系统肿瘤，包括脑膜瘤、室管膜瘤和神经鞘瘤。在此，我们报告了 2 例 NF2 患者的 68Ga-DOTATATE PET/CT 检查结果。
