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母亲饮茶与妊娠高血压风险的关联:中国兰州的一项回顾性队列研究。

The association between maternal tea consumption and the risk of pregnancy induced hypertension: A retrospective cohort study in Lanzhou, China.

机构信息

Department of Pharmacy, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou, Gansu 730050, China.

Department of Pharmacy, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou, Gansu 730050, China.

出版信息

Pregnancy Hypertens. 2022 Dec;30:44-50. doi: 10.1016/j.preghy.2022.08.002. Epub 2022 Aug 6.

Abstract

BACKGROUND

Existing evidence on the relationship between maternal tea consumption and pregnancy induced hypertension (PIH) is inconclusive. This study aimed to evaluate the association between maternal tea consumption and the risk of PIH.

METHODS

This study analysed the data of women without chronic hypertension who participated in a retrospective birth cohort study conducted from 2010 to 2012 at the Gansu Provincial Maternity and Child Care Hospital in Lanzhou, China. Multivariable logistic regression models were used to estimate the association between tea consumption and the risk of PIH and its clinical subtypes by different tea exposure time windows.

RESULTS

Among the 10,452 women included in this study, tea consumption during pregnancy was significantly associated with an increased risk of PIH (odds ratio [OR] = 1.44, 95 % confidence interval [CI]: 1.01, 2.05), gestational hypertension (OR = 1.86, 95 % CI: 1.07, 3.21), and early-onset preeclampsia (OR = 2.93, 95 % CI: 1.21, 7.09). This was especially the case with black tea (OR = 3.57, 95 % CI: 1.67, 7.62).

CONCLUSIONS

Tea consumption during pregnancy might be associated with an increased risk of PIH, gestational hypertension, and early-onset preeclampsia. These findings have important implications for public health in reducing the PIH.

摘要

背景

现有关于母亲饮茶与妊娠高血压(PIH)之间关系的证据尚无定论。本研究旨在评估母亲饮茶与 PIH 风险之间的关联。

方法

本研究分析了 2010 年至 2012 年期间在中国兰州甘肃省妇幼保健院进行的回顾性出生队列研究中未患有慢性高血压的女性的数据。使用多变量逻辑回归模型来估计不同茶暴露时间窗口下饮茶与 PIH 及其临床亚型风险之间的关联。

结果

在本研究纳入的 10452 名女性中,怀孕期间饮茶与 PIH(比值比[OR] = 1.44,95%置信区间[CI]:1.01,2.05)、妊娠期高血压(OR = 1.86,95%CI:1.07,3.21)和早发型子痫前期(OR = 2.93,95%CI:1.21,7.09)的风险显著增加相关。尤其是红茶(OR = 3.57,95%CI:1.67,7.62)。

结论

怀孕期间饮茶可能与 PIH、妊娠期高血压和早发型子痫前期的风险增加相关。这些发现对公共卫生具有重要意义,可以降低 PIH 的风险。

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