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“工作日效应”是否会影响食管癌手术的结果?

The "Weekday Effect"-Does It Impact Esophageal Cancer Surgery Outcomes?

机构信息

Division of Thoracic Surgery, Department of Surgical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.

出版信息

J Gastrointest Cancer. 2023 Sep;54(3):970-977. doi: 10.1007/s12029-022-00855-7. Epub 2022 Aug 13.

Abstract

BACKGROUND

Increased 30-day mortality rates have been reported in patients undergoing elective surgery later compared with earlier in the week. However, these reports have been conflicting for esophageal surgery. We conducted a study to assess the differences in outcomes of patients undergoing surgery for esophageal cancer earlier in the week (Tuesday) versus later (Friday).

METHODS

This retrospective analysis of a prospectively maintained database included patients with esophageal cancer who underwent esophageal resection in a tertiary cancer center between 1 January 2005 and 31 December 2017. We compared patients operated on Tuesdays versus Fridays. The primary outcome was a composite of major morbidity (defined as Clavien-Dindo grade 3 or more) and/or mortality. Secondary outcomes included duration of post-operative ventilation, and length of ICU and hospital stay.

RESULTS

Among 1300 patients included, 733 were operated on a Tuesday and 567 on a Friday. Patient and surgery characteristics were similar in the two groups. The primary outcome (composite of major morbidity and mortality) was 23.6% in the Tuesday group versus 26.3% in the Friday group. Mortality was similar in the two groups (6.0%). Multivariable logistic regression analysis showed that the day of surgery was not a predictor of major morbidity or mortality.

CONCLUSIONS

In patients undergoing esophagectomy at tertiary care high volume cancer center, there was no difference in major morbidity and mortality whether the surgery was performed early in the week (Tuesday) or closer to the weekend (Friday).

摘要

背景

与一周中较早时间相比,择期手术的患者在较晚时间接受手术的 30 天死亡率有所增加。然而,这些报告在食管手术方面存在争议。我们进行了一项研究,以评估在一周中较早时间(星期二)和较晚时间(星期五)接受手术的食管癌症患者的结局差异。

方法

这是一项回顾性分析,对前瞻性维护的数据库进行分析,纳入了 2005 年 1 月 1 日至 2017 年 12 月 31 日期间在三级癌症中心接受食管切除术的食管癌症患者。我们比较了星期二和星期五接受手术的患者。主要结局是主要发病率(定义为 Clavien-Dindo 分级 3 级或更高)和/或死亡率的复合结果。次要结局包括术后通气时间、重症监护病房和住院时间。

结果

在纳入的 1300 名患者中,733 名患者在星期二接受手术,567 名患者在星期五接受手术。两组患者和手术特征相似。主要结局(主要发病率和死亡率的复合结果)在星期二组为 23.6%,在星期五组为 26.3%。两组死亡率相似(6.0%)。多变量逻辑回归分析表明,手术日不是主要发病率或死亡率的预测因素。

结论

在接受三级护理大容量癌症中心食管切除术的患者中,无论手术是在一周中较早时间(星期二)还是更接近周末(星期五)进行,主要发病率和死亡率均无差异。

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