Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Lund, Sweden.
Memory Clinic, Skane University Hospital, Malmö, Sweden.
J Alzheimers Dis. 2022;89(3):865-876. doi: 10.3233/JAD-220233.
The number of people with a migration background and dementia is increasing in Europe. All patients with suspected dementia have the right to an appropriate cognitive assessment and correct diagnosis for optimal treatment and support. Rowland Universal Dementia Assessment Scale (RUDAS) cognitive screening instrument is less affected by language, culture, and educational background, and adapted for use in multicultural populations.
To compare the diagnostic accuracy of RUDAS-S to the Swedish version of Mini-Mental State Examination (MMSE-SR) for detecting dementia in a multicultural group of outpatients in Swedish memory clinics.
We tested 123 outpatients (36 nonnative Swedish), in 4 memory clinics in Southern Sweden with RUDAS-S to supplement the usual cognitive assessment.
RUDAS-S had moderate to good diagnostic performance for detecting dementia in a multicultural population in Sweden, with an area under the receiver operating characteristic curve (AUC) of 0.81. At a cutoff score <25 its sensitivity was 0.92, specificity 0.60, and accuracy 76%. The AUC for the MMSE-SR was 0.79. At a cutoff score <23 its sensitivity was 0.65, specificity 0.81, and accuracy 73%.
RUDAS-S is at least as accurate as MMSE-SR for detecting dementia in memory clinics in Sweden and can be used for all patients undergoing a cognitive assessment, irrespective of their cultural, language, and educational background. However, there is a need for other cross-cultural cognitive tests to complement RUDAS-S to extend cognitive examination.
欧洲有移民背景和痴呆症的人数正在增加。所有疑似痴呆症的患者都有权进行适当的认知评估和正确诊断,以获得最佳的治疗和支持。罗兰普遍痴呆评估量表(RUDAS)认知筛查工具受语言、文化和教育背景的影响较小,适用于多元文化人群。
比较 RUDAS-S 与瑞典版简易精神状态检查(MMSE-SR)在瑞典记忆诊所的多元文化门诊患者中诊断痴呆的准确性。
我们在瑞典南部的 4 家记忆诊所中测试了 123 名门诊患者(36 名非瑞典母语者),使用 RUDAS-S 补充常规认知评估。
RUDAS-S 在瑞典多元文化人群中诊断痴呆的性能为中度至良好,受试者工作特征曲线(ROC)下面积(AUC)为 0.81。在截断分数<25 时,其敏感性为 0.92,特异性为 0.60,准确性为 76%。MMSE-SR 的 AUC 为 0.79。在截断分数<23 时,其敏感性为 0.65,特异性为 0.81,准确性为 73%。
RUDAS-S 在瑞典的记忆诊所中诊断痴呆的准确性至少与 MMSE-SR 相当,可用于所有接受认知评估的患者,无论其文化、语言和教育背景如何。然而,需要其他跨文化认知测试来补充 RUDAS-S,以扩展认知检查。