Dorwal Manisha, Yadav Garima, Singh Pratibha, Kathuria Priyanka, Gothwal Meenakshi, Ghuman Navdeep Kaur, Shekhar Shashank
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Jodhpur, India.
Int J Gynaecol Obstet. 2023 Feb;160(2):698-706. doi: 10.1002/ijgo.14403. Epub 2022 Aug 28.
To derive a prediction model combining various clinical factors associated with increased risk of emergency cesarean section following induction of labor in women with unfavorable cervix.
All women with singleton term pregnancies undergoing induction of labor and fulfilling inclusion criteria were included in this cross-sectional study after supplying consent. Women with a Bishop score of 6 or less were induced with dinoprostone gel. Multiple regression analysis was used to find the most significant independent predictive factors and these factors were used to develop the predictive model and calculator.
After multiple logistic regression, risk of emergency cesarean after induction of labor was significantly associated with the following variables: height (adjusted odds ratio [aOR] 0.955, P = 0.033), nulliparity (aOR 3.987, P < 0.001), closed cervix (aOR 2.030, P = 0.030), fetal station -3 above ischial spine (aOR 2.719, P = 0.043), firm or medium cervical consistency (aOR 2.028, P = 0.004), cervical length 3 cm or longer (aOR 3.090, P = 0.015), posterior cervix (aOR 2.112, P = 0.002).
Use of a prediction model would help to reduce the number of emergency cesarean sections secondary to unsuccessful inductions and help in the reduction of maternal and perinatal morbidity.
建立一个预测模型,该模型结合与宫颈条件不佳的孕妇引产术后急诊剖宫产风险增加相关的各种临床因素。
所有单胎足月妊娠且接受引产并符合纳入标准的孕妇在签署知情同意书后纳入本横断面研究。 Bishop评分6分及以下的孕妇使用地诺前列酮凝胶引产。采用多元回归分析寻找最显著的独立预测因素,并将这些因素用于建立预测模型和计算器。
经过多因素logistic回归分析,引产术后急诊剖宫产风险与以下变量显著相关:身高(调整优势比[aOR]0.955,P = 0.033)、未生育(aOR 3.987,P < 0.001)、宫颈未扩张(aOR 2.030,P = 0.030)、胎儿先露部坐骨棘平面以上-3(aOR 2.719,P = 0.043)、宫颈质地硬或中等(aOR 2.028,P = 0.004)、宫颈长度3cm及以上(aOR 3.090,P = 0.015)、宫颈后位(aOR 2.112,P = 0.002)。
使用预测模型将有助于减少引产失败导致的急诊剖宫产数量,并有助于降低孕产妇和围产儿发病率。