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中国前尿道狭窄的治疗实践:一项基于病例的调查。

The treatment practices for anterior urethral strictures in China: A case-based survey.

作者信息

Hou Changhao, Lin Jiahao, Gu Yubo, Yuan Wei, Wang Zeyu, Xiu Xianjie, Fu Qiang, Song Lujie

机构信息

Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Shanghai Eastern Institute of Urologic Reconstruction, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

出版信息

Front Surg. 2022 Jul 27;9:863463. doi: 10.3389/fsurg.2022.863463. eCollection 2022.

Abstract

OBJECTIVE

To investigate the treatment concept of Chinese urologists for anterior urethral strictures based on actual cases.

METHODS

A self-designed case-based questionnaire was distributed to the members of Official WeChat account of Learning Union from March 19, 2020, to April 10, 2020. Questionnaires requested respondents' demographic information and responses to five cases of anterior urethral stricture: short obliterative bulbar urethral stricture caused by straddle injury (Case 1), idiopathic bulbar urethral stricture after failure of multiple endoscopic therapy (Case 2), iatrogenic long penile urethral stricture (Case 3), lichen sclerosis-related urethral stricture (Case 4), and anterior urethral stricture in indwelling catheter after multiple failure of endoscopic surgery (Case 5). Data was described by frequency and percentage.

RESULTS

A total of 1,267 valid anonymous questionnaires were received. Urethroplasty was recommended more frequently than endoscopic surgery (Case 1: 47.8% vs. 32.8%,Case 2: 42.5% vs. 33.8%, Case 3: 36.1% vs. 26.7%). Referrals patients to other urologists engaged in urethral repair and reconstruction account for a high portion of the treatment (Case 1:18.4%, Case 2:23.1%, Case 3:36.5%, Case 4:27.7%,Case 5:9.3%). Excision and primary anastomosis urethroplasty (EPA) was preferred for treatment of Case 1 (42.5%). For Case 2, the most popular choice was EPA (30.6%). Although the patient has a history of failure in endoscopic surgery, 33.8% of urologists continue to choose endoscopic surgery. For Case 3, 20.0% of urologists would perform oral mucosal urethroplasty. Surprisingly, 5.9% chose EPA. For Case 4, 37.3% of urologists selected meatotomy, 30.4% suggested that glans and urethral biopsies should be performed. 21.0% chose to use steroid ointment after surgery. For Case 5, 26.3% of the respondents believed that urethrography should be performed after removing catheter more than one week, if the urine is obstructed during the period, performing cystostomy firstly.

CONCLUSIONS

In China, the concept of urethroplasty is more widely accepted than endoscopic surgery for the treatment of anterior urethral strictures. The concept of referral has been widely formed among Chinese urologists. Better understanding of the comprehensive treatment of lichen sclerosis related anterior urethral stricture and the principle of urethral rest should be strengthened.

摘要

目的

基于实际病例探讨中国泌尿外科医生对前尿道狭窄的治疗理念。

方法

2020年3月19日至2020年4月10日,向学习联盟官方微信账号成员发放自行设计的基于病例的问卷。问卷要求受访者提供人口统计学信息,并对5例前尿道狭窄病例做出回答:骑跨伤导致的短段闭塞性球部尿道狭窄(病例1)、多次内镜治疗失败后的特发性球部尿道狭窄(病例2)、医源性长段阴茎部尿道狭窄(病例3)、扁平苔藓相关尿道狭窄(病例4)以及内镜手术多次失败后留置导尿管引起的前尿道狭窄(病例5)。数据以频率和百分比描述。

结果

共收到1267份有效匿名问卷。推荐尿道成形术的频率高于内镜手术(病例1:47.8%对32.8%,病例2:42.5%对33.8%,病例3:36.1%对26.7%)。将患者转诊给其他从事尿道修复重建的泌尿外科医生在治疗中占比很高(病例1:18.4%,病例2:23.1%,病例3:36.5%,病例4:27.7%,病例5:9.3%)。病例1的治疗首选切除端端吻合尿道成形术(EPA)(42.5%)。病例2最受欢迎的选择是EPA(30.6%)。尽管患者有内镜手术失败史,但33.8%的泌尿外科医生仍继续选择内镜手术。病例3中,20.0%的泌尿外科医生会进行口腔黏膜尿道成形术。令人惊讶的是,5.9%选择了EPA。病例4中,37.3%的泌尿外科医生选择尿道口切开术,30.4%建议进行龟头和尿道活检。21.0%选择术后使用类固醇软膏。病例5中,26.3%的受访者认为拔除导尿管一周以上后应进行尿道造影,如果在此期间尿液梗阻,应首先进行膀胱造瘘术。

结论

在中国,对于前尿道狭窄的治疗,尿道成形术的理念比内镜手术更广泛地被接受。转诊理念在中国泌尿外科医生中已广泛形成。应加强对扁平苔藓相关前尿道狭窄综合治疗及尿道休息原则的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0c0/9363623/ede4e6baafd7/fsurg-09-863463-g001.jpg

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