体细胞突变在淋巴细胞多样性产生中的作用。 - Suppr | 超能文献

Role of somatic mutation in the generation of lymphocyte diversity.

出版信息

Immunol Rev. 1987 Apr;96:1-162.

Abstract

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B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.B细胞受体介导的CD1d限制性抗原摄取通过在体内募集恒定自然杀伤T细胞辅助来增强抗体反应。

Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8345-50. doi: 10.1073/pnas.0802968105. Epub 2008 Jun 11.

2

Parallel evolution of antibody variable regions by somatic processes: consecutive shared somatic alterations in VH genes expressed by independently generated hybridomas apparently acquired by point mutation and selection rather than by gene conversion.抗体可变区通过体细胞过程的平行进化：独立产生的杂交瘤所表达的VH基因中连续共享的体细胞改变，这些改变显然是通过点突变和选择而非基因转换获得的。

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Interactions between immunogenic peptides and HLA-DR molecules.

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