Department of Community Healthcare and Geriatrics, Nagoya University Hospital, Nagoya, Japan.
Department of Hematology, Nagoya University Hospital, Nagoya, Japan.
Nagoya J Med Sci. 2022 May;84(2):470-476. doi: 10.18999/nagjms.84.2.470.
An 83-year-old man underwent head computed tomography (CT) to investigate cognitive decline and gait disturbance and was admitted to undergo a cerebrospinal fluid (CSF) tap test for suspected idiopathic normal-pressure hydrocephalus. He had a history of chemotherapy for mantle cell lymphoma (MCL), but CT on admission showed no evidence of recurrence. After admission, his level of consciousness rapidly deteriorated and CSF examination suggested infiltration of MCL into the central nervous system (CNS). Although CNS involvement in MCL is rare, this case demonstrates that even if recurrence of MCL is not suspected based on CT findings.
一位 83 岁男性因认知功能减退和步态障碍接受头部计算机断层扫描（CT）检查，拟诊特发性正常压力脑积水而行腰椎穿刺术。患者曾因套细胞淋巴瘤（MCL）接受化疗，但入院 CT 未见复发证据。入院后，患者意识迅速恶化，CSF 检查提示 MCL 累及中枢神经系统（CNS）。尽管 MCL 累及 CNS 较为罕见，但本病例表明，即使 CT 检查结果不提示 MCL 复发，也不能排除 CNS 受累。
