口腔内恶性血管球瘤。

Intraoral malignant glomus tumor.

作者信息

Chandran Satheesh, Elangovan Arun, Vijayakumar Saranya, Kumar K Sai Sarath

机构信息

Department of Oral and Maxillofacial Surgery, Madha Dental College and Hospital, Chennai, Tamil Nadu, India.

Department of Pediatric Dentistry, Madha Dental College and Hospital, Chennai, Tamil Nadu, India.

出版信息

J Oral Maxillofac Pathol. 2022 Apr-Jun;26(2):259-262. doi: 10.4103/jomfp.jomfp_444_21. Epub 2022 Jun 28.

DOI:10.4103/jomfp.jomfp_444_21

PMID:35968168

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9364626/

Abstract

Glomus tumors are uncommon, benign solitary tumors derived from the glomus apparatus. We report here a case of a malignant glomus tumor in an 8-year-old child presenting as a multilocular ill-defined radiolucency of the mandible. The lesion microscopically showed sheets of round basophilic cells with high nuclear-cytoplasmic ratio, indistinct cell boundaries, nuclear hyperchromatism and nuclear pleomorphism. Immunohistochemically, the tumor was positive for vimentin and smooth muscle actin.

摘要

血管球瘤是一种罕见的良性孤立性肿瘤，起源于血管球装置。我们在此报告一例8岁儿童的恶性血管球瘤，表现为下颌骨多房性边界不清的透射区。显微镜下病变显示成片的圆形嗜碱性细胞，核质比高，细胞边界不清，核深染和核多形性。免疫组化显示，肿瘤波形蛋白和平滑肌肌动蛋白呈阳性。