Babu N Aravindha, Anitha N
Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tami Nadu, India.
J Oral Maxillofac Pathol. 2022 Apr-Jun;26(2):144-146. doi: 10.4103/jomfp.jomfp_161_22. Epub 2022 Jun 28.
Oral candidiasis is an opportunistic fungal infection commonly encountered in immunocompromised individuals. The oral cavity harbours numerous microbes and along with immunity saliva also maintains oral health. The Candida species form biofilm over the tissue and prosthetic surfaces. The biofilm formation results in persistent colonisation and persistent infection. The saliva in the oral cavity maintains the integrity of the oral environment by washing away the microbes through its flow and with its antimicrobial agents. The significant role of salivary histatins as an antifungal agent diminishes with hyposalivation. The importance of saliva in preventing fungal colonisation and infection is discussed in this review.
口腔念珠菌病是一种在免疫功能低下个体中常见的机会性真菌感染。口腔中存在大量微生物，唾液连同免疫力一起维持口腔健康。念珠菌属在组织和假体表面形成生物膜。生物膜的形成导致持续定植和持续感染。口腔中的唾液通过其流动和抗菌剂冲走微生物，从而维持口腔环境的完整性。随着唾液分泌减少，唾液组蛋白作为抗真菌剂的重要作用也会减弱。本文综述了唾液在预防真菌定植和感染中的重要性。
