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卫生保健服务的利用、死产以及孟加拉国母婴健康券计划实施后新生儿和婴儿的生存:基于 2000 年至 2016 年孟加拉国人口与健康调查数据的双重差分分析

Health care services use, stillbirth, and neonatal and infant survival following implementation of the Maternal Health Voucher Scheme in Bangladesh: A difference-in-differences analysis of Bangladesh Demographic and Health Survey data, 2000 to 2016.

机构信息

Institute of Health and Social Policy, McGill University, Montréal, Québec, Canada.

Department of Epidemiology, Biostatistics and Occupational Health, Montréal, Québec, Canada.

出版信息

PLoS Med. 2022 Aug 15;19(8):e1004022. doi: 10.1371/journal.pmed.1004022. eCollection 2022 Aug.

DOI:10.1371/journal.pmed.1004022
PMID:35969524
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9377610/
Abstract

BACKGROUND

Starting in 2006 to 2007, the Government of Bangladesh implemented the Maternal Health Voucher Scheme (MHVS). This program provides pregnant women with vouchers that can be exchanged for health services from eligible public and private sector providers. In this study, we examined whether access to the MHVS was associated with maternal health services utilization, stillbirth, and neonatal and infant mortality.

METHODS AND FINDINGS

We used information on pregnancies and live births between 2000 to 2016 reported by women 15 to 49 years of age surveyed as part of the Bangladesh Demographic and Health Surveys. Our analytic sample included 23,275 pregnancies lasting at least 7 months for analyses of stillbirth and between 15,125 and 21,668 live births for analyses of health services use, neonatal, and infant mortality. With respect to live births occurring prior to the introduction of the MHVS, 31.3%, 14.1%, and 18.0% of women, respectively, reported receiving at least 3 antenatal care visits, delivering in a health institution, and having a skilled birth attendant at delivery. Rates of neonatal and infant mortality during this period were 40 and 63 per 1,000 live births, respectively, and there were 32 stillbirths per 1,000 pregnancies lasting at least 7 months. We applied a difference-in-differences design to estimate the effect of providing subdistrict-level access to the MHVS program, with inverse probability of treatment weights to address selection into the program. The introduction of the MHVS program was associated with a lagged improvement in the probability of delivering in a health facility, one of the primary targets of the program, although associations with other health services were less evident. After 6 years of access to the MHVS, the probabilities of reporting at least 3 antenatal care visits, delivering in a health facility, and having a skilled birth attendant present increased by 3.0 [95% confidence interval (95% CI) = -4.8, 10.7], 6.5 (95% CI = -0.6, 13.6), and 5.8 (95% CI = -1.8, 13.3) percentage points, respectively. We did not observe evidence consistent with the program improving health outcomes, with probabilities of stillbirth, neonatal mortality, and infant mortality decreasing by 0.7 (95% CI = -1.3, 2.6), 0.8 (95% CI = -1.7, 3.4), and 1.3 (95% CI = -2.5, 5.1) percentage points, respectively, after 6 years of access to the MHVS. The sample size was insufficient to detect smaller associations with adequate precision. Additionally, we cannot rule out the possibility of measurement error, although it was likely nondifferential by treatment group, or unmeasured confounding by concomitant interventions that were implemented differentially in treated and control areas.

CONCLUSIONS

In this study, we found that the introduction of the MHVS was positively associated with the probability of delivering in a health facility, but despite a longer period of follow-up than most extant evaluations, we did not observe attendant reductions in stillbirth, neonatal mortality, or infant mortality. Further work and engagement with stakeholders is needed to assess if the MHVS has affected the quality of care and health inequalities and whether the design and eligibility of the program should be modified to improve maternal and neonatal health outcomes.

摘要

背景

2006 年至 2007 年,孟加拉国政府实施了孕产妇保健券计划(MHSV)。该计划向孕妇提供凭证,可用于从合格的公共和私营部门提供者那里换取卫生服务。在这项研究中,我们研究了获得 MHSV 是否与孕产妇保健服务的利用、死产以及新生儿和婴儿死亡率有关。

方法和发现

我们使用了孟加拉国人口与健康调查中 15 至 49 岁女性报告的 2000 年至 2016 年期间妊娠和活产的信息。我们的分析样本包括至少持续 7 个月的 23275 例妊娠和 15125 至 21668 例活产,用于分析死产以及卫生服务利用、新生儿和婴儿死亡率。在 MHSV 推出之前发生的活产中,分别有 31.3%、14.1%和 18.0%的妇女报告至少接受了 3 次产前检查、在医疗机构分娩和有熟练的接生员接生。在此期间,新生儿和婴儿死亡率分别为每 1000 例活产 40 例和 63 例,每 1000 例至少持续 7 个月的妊娠中有 32 例死产。我们应用差异中的差异设计来估计向基层提供 MHSV 计划的效果,并使用逆概率治疗权重来解决进入该计划的选择问题。尽管与其他卫生服务的关联不太明显,但 MHSV 计划的推出与在医疗机构分娩的可能性增加有滞后效应,这是该计划的主要目标之一。在获得 MHSV 六年之后,报告至少接受 3 次产前检查、在医疗机构分娩和有熟练的接生员在场的可能性分别增加了 3.0[95%置信区间(95%CI)=-4.8,10.7]、6.5(95%CI=-0.6,13.6)和 5.8(95%CI=-1.8,13.3)个百分点。我们没有发现证据表明该计划改善了健康结果,在获得 MHSV 六年之后,死产、新生儿死亡率和婴儿死亡率的可能性分别降低了 0.7(95%CI=-1.3,2.6)、0.8(95%CI=-1.7,3.4)和 1.3(95%CI=-2.5,5.1)个百分点。样本量不足以准确检测到较小的关联。此外,我们不能排除测量误差的可能性,尽管它可能因治疗组而无差异,或者因在治疗和对照地区实施的同时干预措施而存在未测量的混杂。

结论

在这项研究中,我们发现 MHSV 的引入与在医疗机构分娩的可能性呈正相关,但尽管随访时间比大多数现有评估都要长,我们没有观察到死产、新生儿死亡率或婴儿死亡率相应下降。需要进一步的工作和与利益相关者的接触,以评估 MHSV 是否影响了护理质量和健康不平等,以及是否需要修改该计划的设计和资格标准,以改善孕产妇和新生儿的健康结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/559f47c7fe24/pmed.1004022.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/3a880c3b7437/pmed.1004022.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/37e55cac1512/pmed.1004022.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/de2dd4cc42a8/pmed.1004022.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/559f47c7fe24/pmed.1004022.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/3a880c3b7437/pmed.1004022.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/37e55cac1512/pmed.1004022.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/de2dd4cc42a8/pmed.1004022.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f00/9377610/559f47c7fe24/pmed.1004022.g004.jpg

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