Eleftheriadis E, Dadoukis J, Kotzampassi K, Aletras H
Int Surg. 1987 Jan-Mar;72(1):11-2.
Eight patients from a series of 13 having esophageal resection and colon interposition for benign disease have been evaluated by endoscopic testing, with special emphasis on the mucosal long-term changes of the colon segment and their histologic documentation. The average follow-up period was 7.2 years. All patients were in a satisfactory nutritional state but described problems associated with eating, such as regurgitation of undigested foods and substernal postprandial heartburn. No stricture was present but endoscopy confirmed the existence of food in the haustra. There was no gross evidence of colitis but the histological evaluation revealed inflammatory cell infiltration or fibrosis in all patients but one. It is believed that the main cause of mucosal damage is the prolonged cascading of food and delayed emptying, leading to digestion in the haustra.
在一系列因良性疾病接受食管切除及结肠间置术的13名患者中，对8名患者进行了内镜检查，特别关注结肠段黏膜的长期变化及其组织学记录。平均随访期为7.2年。所有患者营养状况良好，但均描述了与进食相关的问题，如未消化食物反流和餐后胸骨后烧心。未发现狭窄，但内镜检查证实肠袋内存在食物。没有明显的结肠炎证据，但组织学评估显示，除1名患者外，所有患者均有炎性细胞浸润或纤维化。据信，黏膜损伤的主要原因是食物的长时间堆积和排空延迟，导致在肠袋内消化。
