University of Health Sciences, Gulhane Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Emrah Neighborhood, Etlik/Kecioren, Ankara 06018, Turkey.
University of Health Sciences, Gulhane Faculty of Medicine, Department of Neurology, Ankara, Turkey.
Mult Scler Relat Disord. 2022 Nov;67:104099. doi: 10.1016/j.msard.2022.104099. Epub 2022 Aug 9.
The ability to turn while walking is essential for people's activities of daily living. Difficulties in turning while walking are commonly shown in people with multiple sclerosis (PwMS). The figure-of-eight walk test (F8W) is a clinical test assessing walking skill in a curved pathway; however, its reliability and validity have not been systematically examined for PwMS.
The study is aimed to investigate: (1) the test-retest reliability of the F8W in PwMS; (2) the standard error of measurement and minimum detectable change in the F8W times; (3) the concurrent and known-groups validity of the F8W times; and (4) the cut-off times that best discriminate fallers from non-fallers with MS.
This cross-sectional study included 41 PwMS and 33 healthy people. The F8W was performed along with the Timed Up and Go Test (TUG), Berg Balance Scale (BBS), Activities-specific Balance Confidence Scale (ABC), and Expanded Disability Status Scale (EDSS). To determine the test-retest reliability, the F8W was conducted twice, 7-10 days apart. The reliability was assessed using the intraclass correlation coefficient (ICC), Bland-Altman plots, standard error of measurement (SEM), and minimal detectable change (MDC). To examine validity, the correlations between the F8W and the TUG, BBS, ABC, and EDSS were assessed using correlation coefficients, and the completion times of the F8W were compared between PwMS and healthy people, and between fallers and non-fallers with MS. The receiver operating characteristic curve was constructed to determine the optimal F8W cut-off time discriminating fallers from non-fallers with MS.
The F8W had excellent test-retest reliability with an ICC of 0.916. Bland-Altman plots showed high agreement between sessions. The SEM and MDC were found to be 0.45 and 1.25, respectively. The F8W indicated a moderate to strong correlation with other outcome measures (correlation coefficients ranged from -0.596 to 0.839, p<0.05). On the F8W, PwMS had a longer time than healthy people while fallers had a longer time than non-fallers with MS (p<0.001, and p<0.001, respectively). The cut-off time of 8.52 s best discriminated the fallers from non-fallers with MS.
The F8W is a reliable and clinically available measurement tool for walking skill in PwMS.
在日常生活中，人们能够边走路边转身是一项基本能力。多发性硬化症患者（PwMS）通常在行走时转身困难。八字形走测试（F8W）是一种评估曲线行走时行走技能的临床测试；然而，其在 PwMS 中的可靠性和有效性尚未得到系统检查。
本研究旨在探讨：（1）F8W 在 PwMS 中的测试-再测试可靠性；（2）F8W 时间的测量标准误差和最小可检测变化；（3）F8W 时间的同时和已知组有效性；（4）最佳区分 MS 跌倒者和非跌倒者的截断时间。
本横断面研究纳入了 41 名 PwMS 和 33 名健康人。F8W 与计时起立行走测试（TUG）、伯格平衡量表（BBS）、活动特异性平衡信心量表（ABC）和扩展残疾状态量表（EDSS）一起进行。为了确定测试-再测试的可靠性，F8W 分两次进行，两次测试之间相隔 7-10 天。使用组内相关系数（ICC）、Bland-Altman 图、测量标准误差（SEM）和最小可检测变化（MDC）来评估可靠性。为了检查有效性，使用相关系数评估了 F8W 与 TUG、BBS、ABC 和 EDSS 之间的相关性，并比较了 PwMS 和健康人之间以及 MS 跌倒者和非跌倒者之间的 F8W 完成时间。构建受试者工作特征曲线以确定最佳 F8W 截断时间，以区分 MS 跌倒者和非跌倒者。
F8W 具有极好的测试-再测试可靠性，ICC 为 0.916。Bland-Altman 图显示两次测试之间具有高度一致性。SEM 和 MDC 分别为 0.45 和 1.25。F8W 与其他结果测量指标之间呈中度至强相关性（相关系数范围为-0.596 至 0.839，p<0.05）。在 F8W 上，PwMS 比健康人花费的时间更长，而跌倒者比 MS 非跌倒者花费的时间更长（p<0.001，p<0.001，分别）。8.52 秒的截断时间可最佳区分 MS 跌倒者和非跌倒者。
F8W 是一种可靠且临床可用的 PwMS 行走技能测量工具。
