Department of Physical Therapy, School of Health Professions, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel -
Multiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel.
Eur J Phys Rehabil Med. 2017 Dec;53(6):841-847. doi: 10.23736/S1973-9087.17.04599-3. Epub 2017 Mar 13.
The importance of mobility impairments in people with multiple sclerosis (PwMS) denotes a need for valid, reliable, sensitive and feasible clinical measuring tools. The Timed Up-and-Go (TUG) test is a unique mobility measure as it captures other functions apart from walking, i.e., rising out of a chair or turning around an object.
To expand the construct validity of the TUG test in PwMS and determine the ability of the TUG score to discriminate between four levels of disability between fallers, recurrent fallers and non-fallers.
Cross-sectional.
Multiple Sclerosis Center, Sheba Medical Center, Israel.
A total of 285 PwMS (176 women) with a mean disease duration of 8.1±8.1 years.
We retrospectively evaluated and analyzed computerized data of the TUG test, Four Square Step Test (FSST), posturography measures, 2-minute Walk Test (2mWT), Timed 25-foot Walk Test, fall status, Falls Efficacy Scale - International, Modified Fatigue Impact Scale, instrumented cognitive assessment, and the Multiple Sclerosis Walking Scale self-reported questionnaire.
The TUG score of the total sample was 9.3±5.1. In terms of the disability subgroups, significant differences were observed between the four groups with the exception of "very mild" to "mild" groups. In terms of fall status, the MS recurrent fallers demonstrated a significantly slower TUG compared to the MS non-fallers. Strong-modest significant correlation scores were found between the TUG and ambulation tests. The strongest scores were found for the FSST and 2MWT; Pearson's r=0.740, -0.731, respectively.
The current study broadens the evidence supporting the usage of the TUG test to assess walking and balance performance in PwMS regardless of the patient's cognitive status. Furthermore, the test can aid in identifying PwMS who are at a high risk of falling.
The TUG test is an excellent tool used to assess mobility capabilities in PwMS, monitor disease progression and identify potential MS fallers.
行动不便对于多发性硬化症患者（PwMS）意义重大，这意味着需要有效的、可靠的、敏感的和可行的临床测量工具。计时起立行走测试（TUG）是一种独特的移动测量方法，因为它除了行走之外还能捕捉到其他功能，例如从椅子上站起来或绕过物体。
扩展 TUG 测试在 PwMS 中的结构效度，并确定 TUG 评分区分跌倒者、复发性跌倒者和非跌倒者四个残疾水平的能力。
横断面研究。
以色列谢巴医疗中心多发性硬化症中心。
共 285 名 PwMS（176 名女性），平均病程 8.1±8.1 年。
我们回顾性评估和分析了 TUG 测试、四步走测试（FSST）、平衡测试、两分钟步行测试（2mWT）、计时 25 英尺步行测试、跌倒状态、跌倒效能量表-国际版、改良疲劳影响量表、仪器认知评估和多发性硬化症行走量表自我报告问卷的计算机数据。
总样本的 TUG 评分为 9.3±5.1。在残疾亚组方面，除了“轻度”到“轻度”组之外，四个组之间存在显著差异。在跌倒状态方面，多发性硬化症复发性跌倒者的 TUG 明显慢于多发性硬化症非跌倒者。TUG 与步态测试之间存在较强的中度显著相关评分。最强的评分出现在 FSST 和 2mWT 中；Pearson r=0.740，-0.731。
本研究扩展了使用 TUG 测试评估 PwMS 行走和平衡表现的证据，无论患者的认知状态如何。此外，该测试可以帮助识别跌倒风险较高的 PwMS。
TUG 测试是一种评估 PwMS 移动能力、监测疾病进展和识别潜在多发性硬化症跌倒者的优秀工具。
