Department of Community Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
BloodTransfusion Research Center, High Institute for Education and Research in Blood Transfusion, Tehran, Iran.
Transfus Apher Sci. 2023 Feb;62(1):103518. doi: 10.1016/j.transci.2022.103518. Epub 2022 Jul 29.
Plasma protein therapies (PPTs) are a group of medicines extracted from human plasma through fractionation. The manufacture of adequate amounts of PPTs requires a large volume of human plasma. WHO emphasized that whole blood and blood component donations should be voluntary and non-remunerated. So, motivating people to donate plasma is crucial. In this study, we evaluated the impact of social media on motivating blood donors to donate plasma without any compensation and the moderating effects of blood donation history on plasma donation.
we allocated blood donors (n = 501) to intervention and control groups randomly. Participants in the intervention group got educational and motivational messages through a WhatsApp channel. Then, we followed up all participants for six months and registered the information of the plasma donation during this period.
In the intervention group, 6.8% had returned to donate plasma, while this was 2% in the control group (p = 0.016, OR:3.59, 95%CI:1.3-9.89). Among regular blood donors in the intervention group, 17.86% had returned to donate plasma but, no regular donor returned to donate plasma in the control group (p = 0.055). In addition, 10.8% of donors who had academic education in the intervention group returned to donate plasma, although this was 2.54% in the control group (P = 0.0485).
Our findings suggest that the educational interventions have more effects on academically educated donors to motivate them to donate plasma.
血浆蛋白疗法（PPT）是一组通过分离从人血浆中提取的药物。制造足够数量的 PPT 需要大量的人血浆。世界卫生组织强调，全血和血液成分捐献应该是自愿和无偿的。因此，激励人们捐献血浆至关重要。在这项研究中，我们评估了社交媒体对激励无偿献血者捐献血浆的影响，以及献血史对血浆捐献的调节作用。
我们将献血者（n=501）随机分配到干预组和对照组。干预组的参与者通过 WhatsApp 频道获得教育和激励信息。然后，我们对所有参与者进行了六个月的随访，并登记了在此期间的血浆捐献信息。
在干预组中，6.8%的人已经返回捐献血浆，而对照组中这一比例为 2%（p=0.016，OR：3.59，95%CI：1.3-9.89）。在干预组的定期献血者中，17.86%的人已经返回捐献血浆，但对照组中没有定期献血者返回捐献血浆（p=0.055）。此外，干预组中具有学历教育的 10.8%的献血者返回捐献血浆，而对照组中这一比例为 2.54%（P=0.0485）。
我们的研究结果表明，教育干预措施对受过学术教育的献血者更有效果，可激励他们捐献血浆。
