不同浓度管腔内氯化钠溶液对用于手臂输液港植入术的腔内心电图的影响。
Effects of different concentrations of intraluminal sodium chloride solution on intracavitary ECG used for arm infusion port implantation.
机构信息
Five Ward of Oncology Department, The First Affiliated Hospital of Zhengzhou University, Number One, Constructive East Road, Erqi District, Zhengzhou, 450052, China.
Second Department of Internal Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
出版信息
Sci Rep. 2022 Aug 15;12(1):13813. doi: 10.1038/s41598-022-15156-z.
At present, there are few clinical studies on the application of high-concentration sodium chloride solutions in intracavitary ECG-guided catheter tip localization during the arm infusion port implantation. This study observed the effects of sodium chloride solutions with different concentrations on intracavitary ECG-guided arm infusion port implantation in the patients with cancer. The 657 patients receiving arm infusion port implantation in our hospital between January 2020 and August 2021 were randomly divided into 0.9% sodium chloride solution conduction group (group A), 5.45% sodium chloride solution conduction group (group B) and 10% sodium chloride solution conduction group (group C). The derived rate of stable intracavitary ECG, the occurrence rate of characteristic P wave, the time used for catheter tip localization and the optimal position rate of catheter tip were compared between the three groups. The derived rate of stable intracavitary ECG was significantly higher in the group B (97.78%) and group C (98.63%) than in the group A (93.90%) (all P < 0.05). The occurrence rate of characteristic P wave was also significantly higher in the group B (96.89%) and group C (97.72%) than in the group A (88.73%) (all P < 0.001). The time used for catheter tip localization was significantly shorter in the group B [(49.73 ± 8.15) s] and group C [(48.27 ± 8.61) s] than in the group A [(69.37 ± 19.99) s] (all P < 0.001). There was no significant difference in the optimal position rate of catheter tip among the three groups (P > 0.05). The 5.45% and 10% sodium chloride solutions are significantly superior comparing with 0.9% sodium chloride solution in the derived rate of stable intracavitary ECG, occurrence rate of characteristic P wave and time used for catheter tip localization, but there were no significant differences between 5.45 and 10% sodium chloride solutions. Moreover, the 5.45% sodium chloride solution is closer to physiological state comparing with 10% sodium chloride solution, so the 5.45% sodium chloride solution may be recommended for the intracavitary ECG-guided arm infusion port implantation.
目前，关于高浓度氯化钠溶液在腔内心电图引导下导管尖端定位中的应用于手臂输液港植入术的临床研究较少。本研究观察了不同浓度氯化钠溶液对癌症患者腔内心电图引导下手臂输液港植入术的影响。选取我院 2020 年 1 月至 2021 年 8 月间收治的 657 例行手臂输液港植入术的患者，随机分为 0.9%氯化钠溶液组（A 组）、5.45%氯化钠溶液组（B 组）和 10%氯化钠溶液组（C 组）。比较三组患者腔内心电图稳定引出率、特征性 P 波出现率、导管尖端定位时间和导管尖端最佳位置率。B 组和 C 组腔内心电图稳定引出率均明显高于 A 组（97.78%、98.63%比 93.90%）（均 P<0.05）。B 组和 C 组特征性 P 波出现率也明显高于 A 组（96.89%、97.72%比 88.73%）（均 P<0.001）。B 组和 C 组导管尖端定位时间明显短于 A 组[（49.73±8.15）s、（48.27±8.61）s 比（69.37±19.99）s]（均 P<0.001）。三组导管尖端最佳位置率比较差异无统计学意义（P>0.05）。5.45%和 10%氯化钠溶液在稳定腔内心电图引出率、特征性 P 波出现率和导管尖端定位时间方面明显优于 0.9%氯化钠溶液，但 5.45%和 10%氯化钠溶液之间比较差异无统计学意义。而且，5.45%氯化钠溶液与 10%氯化钠溶液相比更接近生理状态，因此推荐在腔内心电图引导下手臂输液港植入术中使用 5.45%氯化钠溶液。
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