Department of Mechanical & Electrical Engineering, Xiamen University, Xiamen 361101, P. R. China.
ACS Appl Mater Interfaces. 2022 Aug 24;14(33):38291-38301. doi: 10.1021/acsami.2c08124. Epub 2022 Aug 15.
Cilia are fundamental functional structures in natural biology. As the primary option of artificial cilia, magnetic cilia have been drawing extensive attention due to their excellent biocompatibility, sensitive response, and contactless actuation. However, most of the ordered magnetic cilia are fabricated by molds, suffering from high cost and low efficiency. In this paper, an ultrafast fabrication method of ordered cilia array using the micro-cavity inducing effect was proposed. With the impact of static and dynamic magnetic fields, the fine cilia were first formed in out-cavity area and then converged above cavities forming complete cilia structures. The mechanism of the micro-cavity inducing effect was further revealed. Finally, the ordered cilia array was used to develop the pressure sensor with variable stiffness, making the in situ adjustment of the sensor performance possible. The ordered cilia array was applied as a micro-mixer and largely improved the mixing efficiency for different mediums. The ordered cilia array also successfully served as the info carrier for rapid sub-encryption. This method allows the fast and controlled forming of ordered cilia arrays within 30 s, and the cilia structure can be adjusted in a large range of aspect ratios (1-9), providing an approach to large-scale producing the magnetic cilia for different applications.
纤毛是自然生物学中的基本功能结构。作为人工纤毛的主要选择，磁性纤毛由于其出色的生物相容性、敏感的响应和非接触式驱动而引起了广泛关注。然而，大多数有序的磁性纤毛都是通过模具制造的，这存在成本高和效率低的问题。本文提出了一种使用微腔诱导效应快速制造有序纤毛阵列的方法。在静态和动态磁场的共同作用下，细小的纤毛首先在外腔区域形成，然后在腔上方汇聚形成完整的纤毛结构。进一步揭示了微腔诱导效应的机制。最后，将有序的纤毛阵列用于开发具有可变刚度的压力传感器，使得传感器性能可以进行原位调整。有序的纤毛阵列被用作微混合器，大大提高了不同介质的混合效率。有序的纤毛阵列还成功地用作快速子加密的信息载体。该方法允许在 30 秒内快速且受控地形成有序纤毛阵列，并且纤毛结构可以在大的纵横比（1-9）范围内进行调整，为不同应用的磁性纤毛的大规模生产提供了一种方法。
