Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Oper Neurosurg (Hagerstown). 2022 Sep 1;23(3):200-205. doi: 10.1227/ons.0000000000000293. Epub 2022 Jun 14.
Persistent cerebrospinal fluid (CSF) egress after durotomy in posterior thoracic or lumbar spine surgery may cause devastating complications. Persistent CSF leaks may require reoperation, which confers additional cost and morbidity.
To evaluate the efficacy of our subfascial epidural drainage protocol in the setting of durotomy to prevent reoperation.
A retrospective cohort study of drained and undrained cohorts was completed to identify factors associated with reoperation for persistent CSF leak-related symptoms. The efficacy and safety of this 7-day subfascial epidural drainage protocol was assessed by comparing reoperation incidence, perioperative complications, rehabilitation necessity, and readmissions.
In total, 156 patients underwent subfascial epidural drainage, and 14 were not drained. Subfascial drainage for up to 7 days was associated with a significantly lower incidence of reoperation than no drainage (3.3% vs 14%, respectively; P = .03). Perioperative complication incidence was similar between cohorts (12.8% vs 21.4%, respectively; P = .37), and length of stay was unchanged regardless of drainage (median 7 days). Subfascial drainage conferred a nearly 2-fold relative risk reduction in inpatient rehabilitation requirement (RR 0.55) and 3-fold relative risk reduction in 30-day (RR 0.31) and 90-day readmission (RR 0.36). Factors associated with reoperation among drained patients included drainage longer than 7 days, tobacco use, age younger than 50 years, and longer segment operations. Revision spine surgery was associated with reoperation among undrained patients.
When followed after durotomy, our subfascial epidural drainage protocol results in fewer reoperations than in an undrained cohort without prohibitive cost and no added morbidity.
后路胸腰椎手术硬脊膜切开后持续的脑脊液(CSF)漏出可能导致灾难性的并发症。持续性 CSF 漏可能需要再次手术,这会带来额外的成本和发病率。
评估我们的筋膜下硬膜外引流方案在硬脊膜切开术后预防再次手术的效果。
完成了引流和未引流队列的回顾性队列研究,以确定与持续性 CSF 漏相关症状相关的再次手术的相关因素。通过比较再次手术发生率、围手术期并发症、康复需要和再入院,评估这种 7 天筋膜下硬膜外引流方案的疗效和安全性。
共有 156 例患者接受了筋膜下硬膜外引流,其中 14 例未引流。筋膜下引流长达 7 天与无引流相比,再次手术的发生率明显较低(分别为 3.3%和 14%,P =.03)。两个队列的围手术期并发症发生率相似(分别为 12.8%和 21.4%,P =.37),无论是否引流,住院时间均保持不变(中位数为 7 天)。筋膜下引流使住院康复需求的相对风险降低近 2 倍(RR 0.55),30 天(RR 0.31)和 90 天(RR 0.36)再入院的相对风险降低 3 倍。在引流患者中,与再次手术相关的因素包括引流时间超过 7 天、吸烟、年龄小于 50 岁以及手术节段较长。未引流患者中,翻修脊柱手术与再次手术相关。
在硬脊膜切开术后使用我们的筋膜下硬膜外引流方案,与未引流组相比,再次手术的发生率更低,且不会增加成本和发病率。