Department of Analytical Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran.
Department of Analytical Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran; Institute of Nanotechnology, Urmia University, Urmia, Iran.
Food Chem. 2023 Jan 1;398:133910. doi: 10.1016/j.foodchem.2022.133910. Epub 2022 Aug 10.
Riboflavin (Rf), an externally supplied nutrient, is highly photosensitive, and should be protected from sunlight once used in food and pharmaceutical manufacturing. The applications of encapsulated Rf have recently developed due to their therapeutic properties. In this study, the use of green silver nanoparticles (AgNPs) synthesized by Rosa damascena mill L. extract to control the encapsulation efficiency of Rf in potato starch was demonstrated for the first time. Starch/Rf, Starch/AgNPs/Rf and Starch/AgNPs nanocapsules were characterized by Fourier-transform infrared, field emission scanning electron microscopy, differential scanning calorimetry, and brunauer-Emmett-Teller techniques. The obtained results showed that the presence of AgNPs reduces Rf nanocapsules size (from 340 to 327 nm), increases the encapsulation efficiency (21.14 ± 0.62 to 92.52 ± 1.32 %) and improves the thermal stability, antibacterial and antioxidant activities. Moreover, UV-vis spectroscopy demonstrated the stronger association of AgNPs/Rf and AgNPs/Rf/Starch nanocapsules with BSA under physiological conditions.
核黄素（Rf）是一种外源性营养物质，对光高度敏感，一旦用于食品和制药生产，就应避光保存。由于其治疗特性，封装的 Rf 的应用最近得到了发展。在这项研究中，首次展示了用玫瑰（Rosa damascena mill L.）提取物合成的绿色银纳米粒子（AgNPs）来控制 Rf 在马铃薯淀粉中的包封效率。通过傅里叶变换红外光谱、场发射扫描电子显微镜、差示扫描量热法和 Brunauer-Emmett-Teller 技术对淀粉/Rf、淀粉/AgNPs/Rf 和淀粉/AgNPs 纳米胶囊进行了表征。结果表明，AgNPs 的存在减小了 Rf 纳米胶囊的粒径（从 340 纳米减小到 327 纳米），提高了包封效率（从 21.14±0.62%提高到 92.52±1.32%），并提高了热稳定性、抗菌和抗氧化活性。此外，紫外可见光谱表明，在生理条件下，AgNPs/Rf 和 AgNPs/Rf/Starch 纳米胶囊与 BSA 的结合更强。
