Solaiman Rafat H, Ogilvie Christian M
Orthopedic Surgery, University of Minnesota Medical School, Minneapolis, USA.
Cureus. 2022 Jul 14;14(7):e26847. doi: 10.7759/cureus.26847. eCollection 2022 Jul.
Phosphaturic mesenchymal tumors (PMT) are a rare neoplasm oftentimes associated with tumor-induced osteomalacia (TIO). The non-specific presentation and symptoms of these pathologies make them difficult to diagnose. We report a case of a 52-year-old patient with an intermetatarsal phosphaturic mesenchymal tumor who presented to the orthopedic sports medicine clinic with metabolic deficiencies and bilateral subtrochanteric cortical stress fractures indicative of osteomalacia. The tumor was entirely resected within nine months of symptom onset and has shown no recurrence at the one-year follow-up. This case report characterizes an unusual cause of stress fractures presenting to orthopedic sports medicine clinics and the variability in the presentation of phosphaturic mesenchymal tumors.
磷尿性间叶肿瘤(PMT)是一种罕见的肿瘤,常与肿瘤诱导的骨软化症(TIO)相关。这些病症的非特异性表现和症状使其难以诊断。我们报告一例52岁患有跖骨间磷尿性间叶肿瘤的患者,该患者因代谢缺陷和双侧转子下皮质应力性骨折(提示骨软化症)就诊于骨科运动医学诊所。肿瘤在症状出现后的九个月内被完全切除,在一年的随访中未显示复发。本病例报告描述了骨科运动医学诊所中应力性骨折的一种不寻常病因以及磷尿性间叶肿瘤表现的变异性。