Linder C W
J Fam Pract. 1978 Oct;7(4):697-700.
A comparison of the treatment of superficial skin infections using intramuscular benzathine penicillin G alone or combined with hexachlorophene scrubbing was conducted in 127 children. Of 72 children treated with benzathine penicillin alone, 94.4 percent had a good result. Of the 55 children receiving hexachlorophene scrubbing in addition to penicillin, 85.5 percent had a good result. The healing rate was higher (93 percent) in those children whose skin cultures grew Group A beta hemolytic streptococci. When staphylococcus aureus was the only pathogen isolated, the healing rate was 86 percent. Regardless of the pathogens isolated, the healing rate was not increased with scrubbing. Since scrubbing with hexachlorophene offered no improvement in the healing rate and since it adds to the expense and discomfort of treatment, it should be eliminated as part of the treatment.
对127名儿童进行了一项关于单独使用苄星青霉素G肌肉注射或联合六氯酚擦洗治疗浅表皮肤感染的比较研究。在仅接受苄星青霉素治疗的72名儿童中,94.4%取得了良好效果。在除青霉素外还接受六氯酚擦洗的55名儿童中,85.5%取得了良好效果。皮肤培养出A组β溶血性链球菌的儿童愈合率更高(93%)。当分离出的唯一病原体是金黄色葡萄球菌时,愈合率为86%。无论分离出何种病原体,擦洗都不会提高愈合率。由于用六氯酚擦洗并不能提高愈合率,而且还增加了治疗费用和不适感,因此应将其从治疗方案中去除。