Department of Pediatric Surgery, Fırat University School of Medicine, Elazig, Turkey.
Department of Pediatrics-Neonatology, Fırat University School of Medicine, Elazig, Turkey.
Niger J Clin Pract. 2022 Aug;25(8):1227-1232. doi: 10.4103/njcp.njcp_1529_21.
Peritoneal dialysis (PD) is frequently used in pediatric patients with renal failure.
In the present study, we evaluated the indications and complications of PD and patients' outcomes in pediatric patients.
Medical records of patients who underwent PD between 2012 and 2019 were analyzed retrospectively. The patients were divided into two groups as acute PD (APD) (Group 1) and chronic PD (CPD) (Group 2). If the patient was diagnosed with acute kidney injury (AKI), an APD catheter was inserted, while a CPD catheter was inserted for patients with stage 5 chronic renal failure or those in which AKI persisted for more than 6 weeks.
Group 1 and Group 2 consisted of 62 and 64 patients, respectively. The most common indications for PD were AKI (64.5%) in Group 1, and obstructive uropathy and reflux nephropathy (45.3%) in Group 2. The overall complication rate was 30%. These were leakage at the catheter insertion site (11.2%), catheter occlusion (4.8%), and peritonitis (4.8%) in Group 1; and peritonitis (14.1%), catheter occlusion (6.2%), and inguinal hernia (4.6%) in Group 2. The mortality rate was 72.5% and 23.4% in Group 1 and Group 2, respectively. The most common causes of mortality were multisystem organ failure (40%) and sepsis (33.5%) in both groups. A total of 83 patients (32 in Group 1 and 51 in Group 2) had omentectomy. Catheter revision and/or removal were performed in 11.9% of all patients. Omentectomy had no effect on the prevention of catheter occlusion (p > 0.05).
The mortality rate is lower in CPD patients than in APD patients. Although PD in pediatric patients is associated with potential complications, its actual rate is relatively low. The primary catheter dysfunction rate is low, and omentectomy has no significant effect on preventing catheter occlusion.
腹膜透析(PD)在肾衰竭的儿科患者中经常使用。
本研究评估了 PD 的适应证和并发症以及儿科患者的结局。
回顾性分析 2012 年至 2019 年期间行 PD 的患者的病历。患者分为两组:急性 PD(APD)(第 1 组)和慢性 PD(CPD)(第 2 组)。如果患者诊断为急性肾损伤(AKI),则插入 APD 导管,而对于 5 期慢性肾衰竭或 AKI 持续超过 6 周的患者,则插入 CPD 导管。
第 1 组和第 2 组分别包括 62 例和 64 例患者。PD 的最常见适应证是第 1 组的 AKI(64.5%),第 2 组的梗阻性尿路病和反流性肾病(45.3%)。总体并发症发生率为 30%。第 1 组有导管插入部位漏液(11.2%)、导管阻塞(4.8%)和腹膜炎(4.8%);第 2 组有腹膜炎(14.1%)、导管阻塞(6.2%)和腹股沟疝(4.6%)。第 1 组和第 2 组的死亡率分别为 72.5%和 23.4%。两组最常见的死亡原因是多器官功能衰竭(40%)和败血症(33.5%)。共有 83 例患者(第 1 组 32 例,第 2 组 51 例)行网膜切除术。所有患者中有 11.9%行导管修正和/或拔除。网膜切除术对预防导管阻塞无影响(p>0.05)。
CPD 患者的死亡率低于 APD 患者。虽然儿科患者 PD 存在潜在并发症,但实际发生率相对较低。原发性导管功能障碍发生率较低,网膜切除术对预防导管阻塞无显著影响。