Cardiology, Prof. Dr A. İlhan Özdemir Training and Research Hospital, Giresun University, Giresun, Turkey.
Cardiology, Balıkesir Ataturk City Hospital, Balıkesir, Turkey.
Angiology. 2023 Jul;74(6):569-578. doi: 10.1177/00033197221114087. Epub 2022 Aug 17.
Ramadan interferes with circadian rhythms mainly by disturbing the routine patterns of feeding and smoking. The objective of this study was to investigate the circadian pattern of ST elevation acute myocardial infarction (STEMI) during the month of Ramadan. We studied consecutive STEMI patients 1 month before and after Ramadan (non-Ramadan group-NRG) and during Ramadan (Ramadan group-RG). The RG group was also divided into two groups, based on whether they chose to fast: fasting (FG) and non-fasting group (NFG). The time of STEMI onset was compared. A total of 742 consecutive STEMI patients were classified into 4 groups by 6 h intervals according to time-of-day at symptom onset. No consistent circadian variation in the onset of STEMI was observed both between the RG ( = .938) and NRG ( = .766) or between the FG ( = .232) and NFG ( = .523). When analyzed for subgroups of the study sample, neither smoking nor diabetes showed circadian rhythm. There was a trend towards a delay from symptom onset to hospital presentation, particularly at evening hours in the RG compared with the control group. In conclusion, there was no significant difference in STEMI onset time, but the time from symptom onset to hospital admission was significantly delayed during Ramadan.
斋月主要通过扰乱进食和吸烟的常规模式来干扰昼夜节律。本研究旨在调查斋月期间 ST 段抬高型急性心肌梗死（STEMI）的昼夜节律模式。我们研究了斋月前后（非斋月组-NRG）和斋月期间（斋月组-RG）连续发生的 STEMI 患者。根据是否选择斋戒，将 RG 组进一步分为禁食组（FG）和不禁食组（NFG）。比较了 STEMI 发病时间。根据症状发作时的时间，将 742 例连续 STEMI 患者分为 4 组，每组 6 小时。在 RG（ =.938）和 NRG（ =.766）或 FG（ =.232）和 NFG（ =.523）之间，STEMI 的发病时间均无一致的昼夜变化。对研究样本的亚组进行分析时，无论是吸烟还是糖尿病，均未显示出昼夜节律。与对照组相比，在 RG 中，从症状发作到入院就诊的时间有延迟的趋势，尤其是在傍晚时段。总之，STEMI 发病时间无明显差异，但在斋月期间，从症状发作到入院的时间明显延迟。
