Department of Dermatology, Habib Thameur Hospital, Tunis, Tunisia;
Research Unit "Genodermatoses and Cancers" LR-12SP03, Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, Tunis, Tunisia.
Skinmed. 2022 Aug 31;20(4):305-306. eCollection 2022.
A 4-year-old boy born from a consanguineous marriage was referred to our department for congenital ichthyosis. He was a collodion baby at birth and progressively developed a generalized erythroderma with fine whitish scales covering his body. Initially, he was diagnosed as having congenital ichthyosiform erythroderma. Physical examination revealed fine white grayish scales with an erythematous background involving the scalp and flexural areas (Figure 1a). His palms and soles depicted hyperlinearity (Figure 1b). His hair, teeth, nails, and mucosa were normal. Abdominal examination revealed hepatomegaly, and the liver was enlarged by 4 cm below the right costal margin. He had a normal motor and mental development, and his neurologic examination was normal. There was no muscular weakness. (. 2022;20:305-306).
一位 4 岁的男孩，出生于近亲婚姻，因先天性鱼鳞病就诊于我科。他出生时为胶样儿，随后逐渐出现全身红斑、细小白色鳞屑。起初，他被诊断为先天性鱼鳞病样红皮病。体格检查显示头皮和屈侧有细小灰白色鳞屑，伴红斑（图 1a）。他的手掌和足底有过度的皮纹（图 1b）。他的毛发、牙齿、指甲和黏膜均正常。腹部检查发现肝大，肋缘下肝肿大 4cm。他的运动和智力发育正常，神经系统检查正常，无肌肉无力。
