DVM., PhD. Konkuk University - College of Veterinary Medicine - Department of Veterinary Surgery - Seoul, South Korea.
DVM. Konkuk University - College of Veterinary Medicine - Department of Veterinary Surgery - Seoul, South Korea.
Acta Cir Bras. 2022 Aug 12;37(5):e370502. doi: 10.1590/acb370502. eCollection 2022.
To identify an optimal self-expandable metallic stent (SEMS) and verify whether a mechanically superior SEMS would result in better clinical outcomes in the treatment of tracheal collapse.
We selected three SEMS (n = 8 each), including an S-type stent with a wire diameter of 0.006 inches (S6) and two D-type stents with wire diameters of 0.006 (D6) and 0.007 inches (D7). Twenty-four New Zealand White rabbits were divided into three equal groups. After the stents were deployed, the clinical signs were recorded daily, and radiographic examinations were performed monthly. All rabbits were euthanized after three months.
Two rabbits with S6 stents and one rabbit with a D7 stent died within three months because of stent migration or pneumonia. All rabbits with D6 stents survived for three months. On histological examination, the D6 group had the lowest inflammation score.
Both clinically and histopathologically, the results with D-type stents with a wire diameter of 0.006 inches were superior to those of the other groups (p = 0.001). The use of an optimal intraluminal stent may improve the long-term clinical outcomes in the treatment of tracheal collapse in dogs.
确定最佳自膨式金属支架（SEMS），并验证在治疗气管塌陷中，机械性能更优的 SEMS 是否会带来更好的临床结果。
我们选择了三种 SEMS（每组各 8 个），包括线径为 0.006 英寸的 S 型支架（S6）和两种线径为 0.006 英寸（D6）和 0.007 英寸（D7）的 D 型支架。将 24 只新西兰白兔分为三组。支架扩张后，每天记录临床症状，每月进行影像学检查。三个月后所有兔子均被安乐死。
2 只 S6 支架的兔子和 1 只 D7 支架的兔子在三个月内因支架移位或肺炎死亡。所有 D6 支架的兔子均存活了三个月。组织学检查发现，D6 组的炎症评分最低。
从临床和组织病理学角度来看，线径为 0.006 英寸的 D 型支架的结果均优于其他两组（p = 0.001）。使用最佳的腔内支架可能会改善治疗犬气管塌陷的长期临床结果。
