Lasry J C, Margolese R G, Poisson R, Shibata H, Fleischer D, Lafleur D, Legault S, Taillefer S
J Chronic Dis. 1987;40(6):529-34. doi: 10.1016/0021-9681(87)90010-5.
A twenty year debate about the appropriate surgery for breast cancer has resulted in two clinical trials comparing radical vs more conservative operations. Despite the favorable results of these trials, the majority of breast cancer patients in North America still undergo mastectomy. We investigated the psychological and social adjustment following total and partial mastectomy in a group of patients randomly assigned to one or the other operation (National Surgical Adjuvant Breast Protocol--B-06). Total mastectomy patients showed higher levels of depression and less satisfaction with body image. Partial mastectomy patients did not display any measurable increase in fear of recurrence. Patients undergoing radiation therapy showed surprising increase in depressive symptoms. Radiation therapy could well be more frightening to breast surgery patients than had been anticipated. These patients may benefit from some anticipatory counselling.
一场关于乳腺癌合适手术方式的二十年辩论促成了两项比较根治性手术与更保守手术的临床试验。尽管这些试验取得了良好结果,但北美大多数乳腺癌患者仍接受乳房切除术。我们在一组随机分配接受全乳房切除术或部分乳房切除术的患者中(国家外科辅助乳腺项目——B - 06),调查了全乳房切除术和部分乳房切除术后的心理和社会适应情况。全乳房切除术患者的抑郁水平较高,对身体形象的满意度较低。部分乳房切除术患者对复发的恐惧没有任何可测量的增加。接受放射治疗的患者抑郁症状出现惊人的增加。放射治疗对乳房手术患者可能比预期更具威慑力。这些患者可能会从一些术前咨询中受益。