威尔逊氏病，一种可逆性痴呆：病例报告。

Wilson's disease, a reversible dementia: case report.

作者信息

Rosselli M, Lorenzana P, Rosselli A, Vergara I

出版信息

J Clin Exp Neuropsychol. 1987 Aug;9(4):399-406. doi: 10.1080/01688638708405060.

Abstract

A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in her dementia and in her motor signs. A second battery of neuropsychological tests demonstrated the improvement in the mental aspects. These findings support the concept of Wilson's disease being a reversible dementia.

摘要

本文报告一例具有明显痴呆特征的晚期威尔逊氏病病例。治疗前的神经心理学评估显示存在智力衰退，尤其是在记忆和执行任务方面。该患者接受了青霉胺（一种铜螯合剂）治疗7个月，其痴呆症状和运动体征有显著改善。第二轮神经心理学测试表明其心理方面有所改善。这些发现支持了威尔逊氏病是一种可逆性痴呆的概念。