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急性 ST 段抬高型心肌梗死患者药物洗脱支架应用的差异:全国住院患者样本分析。

Disparities in Drug-Eluting Stent Utilization in Patients With Acute ST-Elevation Myocardial Infarction: An Analysis of the National Inpatient Sample.

机构信息

Division of Cardiology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Division of Cardiology, Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

出版信息

Angiology. 2023 Sep;74(8):774-782. doi: 10.1177/00033197221121027. Epub 2022 Aug 17.

Abstract

The superiority of drug-eluting stents (DES) compared with bare-metal stents (BMS) is well-established, but data regarding DES use in ST-elevation myocardial infarction (STEMI) as a function of race is limited. Our goal was to examine stent utilization patterns and disparities based on race, sex, and insurance status in patients with STEMI undergoing percutaneous coronary intervention. The National Inpatient Sample database was used to retrospectively compare DES vs BMS use in patients admitted with STEMI from 2009 to 2018. Multivariable logistic regression was performed to assess the independent predictors of DES use. DES utilization increased significantly from 62.8% in 2009 to 94.0% in 2018. However, African Americans were less likely to receive a DES (odds ratio [OR] .82, 95% confidence interval [CI] .77-.87) compared with Caucasians. Women were more likely to undergo DES implantation (OR 1.07, 95% CI 1.05-1.10). Patients insured by Medicaid (OR .84, 95% CI .80-.89) and those classified as Self-pay (OR .63, 95% CI .61-.66) were less likely to undergo DES implantation compared to those with private insurance (OR 1.33, 95% CI 1.29-1.38). Disparities based on race and insurance status continue to persist despite a significant increase in DES utilization in STEMI patients across the identified subgroups.

摘要

药物洗脱支架(DES)与裸金属支架(BMS)相比具有明显优势,然而,关于种族与 ST 段抬高型心肌梗死(STEMI)患者中 DES 使用的数据有限。我们的目标是检查经皮冠状动脉介入治疗(PCI)的 STEMI 患者中基于种族、性别和保险状况的支架使用模式和差异。本研究使用国家住院患者样本数据库,回顾性比较了 2009 年至 2018 年 STEMI 住院患者中使用 DES 和 BMS 的情况。多变量逻辑回归用于评估 DES 使用的独立预测因素。DES 的使用率从 2009 年的 62.8%显著增加到 2018 年的 94.0%。然而,与白人相比,非裔美国人接受 DES 的可能性较低(比值比[OR].82,95%置信区间[CI].77-.87)。女性更有可能接受 DES 植入(OR 1.07,95% CI 1.05-1.10)。与私人保险患者相比,接受医疗补助(OR.84,95% CI.80-.89)和自付(OR.63,95% CI.61-.66)保险的患者接受 DES 植入的可能性较低(OR 1.33,95% CI 1.29-1.38)。尽管在确定的亚组中,STEMI 患者中 DES 的使用率显著增加,但基于种族和保险状况的差异仍然存在。

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