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猫纹状皮层IV层外侧膝状体A板层突触的超微结构

Ultrastructure of synapses from the A-laminae of the lateral geniculate nucleus in layer IV of the cat striate cortex.

作者信息

Einstein G, Davis T L, Sterling P

出版信息

J Comp Neurol. 1987 Jun 1;260(1):63-75. doi: 10.1002/cne.902600106.

DOI:10.1002/cne.902600106
PMID:3597835
Abstract

The morphology of synapses in layer IV of the cat striate cortex was studied by electron microscope (EM) autoradiography of serial sections following injection of tritiated amino acids into the lateral geniculate nucleus. Of the terminals in the neuropil, 22% had 2 or more silver grains in 10 successive sections and were labeled at 8-80 times the background level. These terminals were considered to be specifically labeled and to be derived from the lateral geniculate. Two forms of geniculate synapse were observed. One had medium-size, round vesicles and a modest postsynaptic asymmetry (RA); the other had smaller, pleomorphic vesicles and hardly any postsynaptic opacity; that is, it appeared symmetrical (PS). The geniculate RA terminals were presynaptic to dendritic spines, fine processes, and cell bodies; the geniculate PS terminals were presynaptic to dendrites and cell bodies but not to spines. The possible sources of geniculate PS terminals are discussed.

摘要

通过向外侧膝状体核注射氚标记氨基酸后对连续切片进行电子显微镜(EM)放射自显影,研究了猫纹状皮层IV层突触的形态。在神经毡中的终末中,22%在连续10个切片中有2个或更多银颗粒,标记水平为背景水平的8 - 80倍。这些终末被认为是特异性标记的,并且来自外侧膝状体。观察到两种形式的膝状体突触。一种具有中等大小的圆形囊泡和适度的突触后不对称性(RA);另一种具有较小的、多形性囊泡且几乎没有突触后不透明度;也就是说,它看起来是对称的(PS)。膝状体RA终末位于树突棘、细突起和细胞体的突触前;膝状体PS终末位于树突和细胞体的突触前,但不位于棘的突触前。讨论了膝状体PS终末的可能来源。

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Ultrastructure of synapses from the A-laminae of the lateral geniculate nucleus in layer IV of the cat striate cortex.猫纹状皮层IV层外侧膝状体A板层突触的超微结构
J Comp Neurol. 1987 Jun 1;260(1):63-75. doi: 10.1002/cne.902600106.
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Pattern of lateral geniculate synapses on neuron somata in layer IV of the cat striate cortex.猫纹状皮层IV层神经元胞体上外侧膝状体突触的模式。
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Synaptic reorganization in the dorsal lateral geniculate nucleus following damage to visual cortex in newborn or adult cats.新生或成年猫视觉皮层受损后外侧膝状体背核的突触重组
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The GABA-immunoreactive neurons in the interlaminar regions of the cat lateral geniculate nucleus: light and electron microscopic observations.猫外侧膝状体核层间区域的γ-氨基丁酸免疫反应性神经元:光镜和电镜观察
Exp Brain Res. 1989;75(3):497-512. doi: 10.1007/BF00249901.
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Delayed reduction in GABA and GAD immunoreactivity of neurons in the adult monkey dorsal lateral geniculate nucleus following monocular deprivation or enucleation.
成年猴子单眼剥夺或眼球摘除后,背外侧膝状核中神经元的γ-氨基丁酸(GABA)和谷氨酸脱羧酶(GAD)免疫反应性延迟降低。
Exp Brain Res. 1991;86(1):47-59. doi: 10.1007/BF00231039.