Janus 激酶-1/2 抑制剂治疗难治性类天疱疮样扁平苔藓有效。
Effective treatment of refractory lichen planus pemphigoides with a Janus kinase-1/2 inhibitor.
机构信息
Sinclair Dermatology, East Melbourne, VIC, Australia.
University of Melbourne, Melbourne, VIC, Australia.
出版信息
Clin Exp Dermatol. 2022 Nov;47(11):2040-2041. doi: 10.1111/ced.15344. Epub 2022 Aug 18.
PMID:35980165
Abstract
Lichen planus pemphigoides is a rare autoimmune subepidermal blistering disease clinically and histopathologically characterized by features of lichen planus and bullous pemphigoid. We describe a case of refractory lichen planus pemphigoides successfully treated with the selective and reversible Janus kinase-1/2 inhibitor, baricitinib.
摘要
天疱疮样扁平苔藓是一种罕见的自身免疫性表皮下水疱性疾病，临床上和组织病理学上的特征是扁平苔藓和大疱性类天疱疮。我们描述了一例难治性天疱疮样扁平苔藓成功地用选择性和可逆的 Janus 激酶-1/2 抑制剂巴瑞替尼治疗。
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