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早期口服术后喂养对胃肠道手术后肠动力恢复的影响:系统评价和荟萃分析方案。

The effect of early oral postoperative feeding on the recovery of intestinal motility after gastrointestinal surgery: Protocol for a systematic review and meta-analysis.

机构信息

Dipartimento di Diagnostica e Sanità Pubblica, Università degli Studi di Verona, Verona, Italy.

Corso di Laurea in Infermieristica, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

出版信息

PLoS One. 2022 Aug 18;17(8):e0273085. doi: 10.1371/journal.pone.0273085. eCollection 2022.

Abstract

BACKGROUND

Given the ever-shorter length of hospital stay after surgical procedures, nowadays it is more important than ever to study interventions that may have an impact on surgical patients' wellbeing. According to the ERAS (Enhanced Recovery After Surgery protocols) program, early feeding must be considered one of the key components to facilitate early recovery while improving outcomes and patients' overall experiences. To date, the international literature has reported that early postoperative feeding compared with traditional (or late) timing is safe; nevertheless, small clinical outcomes effects has been reported, also for recovery of gastrointestinal function. Therefore, the effectiveness of early postoperative feeding to reduce postoperative ileus duration remains still debated.

OBJECTIVE

To analyse the effects of early versus delayed oral feeding (liquids and food) on the recovery of intestinal motility after gastrointestinal surgery.

SEARCH METHODS

Pubmed, Embase, Cinahl, Cochrane Central Register of Controlled Trials (CENTRAL), and the ClincalTrials.gov register will be searched to identify the RCTs of interest.

STUDY INCLUSION

Randomized clinical trials (RCTs) comparing the effect of early postoperative versus late oral feeding on major postoperative outcomes after gastrointestinal surgery will be included.

DATA COLLECTION AND ANALYSIS

Two review authors will independently screen titles and abstracts to determine the initially selected studies' inclusion. Any disagreements will be resolved through discussion and consulting a third review author. The research team members will then proceed with the methodological evaluation of the studies and their eligibility for inclusion in the systematic review.

摘要

背景

鉴于手术后住院时间越来越短,研究可能对手术患者的健康产生影响的干预措施比以往任何时候都更为重要。根据 ERAS(手术后强化康复)方案,早期喂养必须被视为促进早期康复、改善结果和患者整体体验的关键组成部分之一。迄今为止,国际文献报告称,与传统(或晚期)时间相比,早期术后喂养是安全的;然而,对于胃肠道功能的恢复,也报告了较小的临床结果影响。因此,早期术后喂养减少术后肠梗阻持续时间的有效性仍存在争议。

目的

分析胃肠手术后早期与延迟口服喂养(液体和食物)对肠道蠕动恢复的影响。

检索方法

将在 Pubmed、Embase、Cinahl、Cochrane 中央对照试验注册中心(CENTRAL)和 ClinicalTrials.gov 登记处搜索以确定相关的 RCT。

研究纳入

将纳入比较胃肠手术后早期术后与晚期口服喂养对主要术后结局影响的随机临床试验(RCT)。

数据收集和分析

两名综述作者将独立筛选标题和摘要,以确定最初选择的研究的纳入情况。任何分歧将通过讨论和咨询第三位综述作者来解决。然后,研究团队成员将对研究进行方法学评估,并确定其是否符合系统综述的纳入标准。

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本文引用的文献

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Reducing ileus after colorectal surgery: A network meta-analysis of therapeutic interventions.
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The clinical and economical impact of postoperative ileus in patients undergoing colorectal surgery.
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Nutritional interventions to improve recovery from postoperative ileus.
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Postoperative ileus following major colorectal surgery.
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