Patel Vandan, Gendler Liya, Barakat Jude, Lim Ryan, Guariento Andressa, Chang Benjamin, Nguyen Jie C
College of Medicine, Drexel University, Philadelphia, PA, USA.
Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Skeletal Radiol. 2023 Feb;52(2):167-174. doi: 10.1007/s00256-022-04156-9. Epub 2022 Aug 19.
To compare the diagnostic accuracy and interpretation time for detection of pediatric fractures on hand radiographs with and without localization cues.
Consecutive children, who underwent radiographic examinations after injury, over 2 years (2019-2021) and with > 2 weeks of follow-up to confirm the presence or absence of a fracture, were included. Four readers, blinded to history and diagnosis, retrospectively reviewed all images twice, without and with cue, at least 1 week apart and after randomization, to determine the presence or absence of a fracture, and if present, anatomic location and diagnostic confidence were recorded. Interpretation time for each study was also recorded and averaged across readers. Inter-reader agreement was calculated using Fleiss' kappa. Diagnostic accuracy and interpretation time were compared between examinations using sensitivity, specificity, and Mann-Whitney U correlation.
Study group included 92 children (61 boys, 31 girls; 10.8 ± 3.4 years) with and 40 (31 boys, 9 girls; 10.9 ± 3.7 years) without fractures. Cue improved inter-reader agreement (κ = 0.47 to 0.62). While the specificity decreased (63 to 62%), sensitivity (75 to 78%), diagnostic accuracy (71 to 73%), and confidence improved (78 to 87%, p < 0.01), and interpretation time (median: 40 to 22 s, p < 0.001) reduced with examinations with localization cue. Specifically, examinations with fracture and cue had the shortest interpretation time (median: 16 s), whereas examinations without fracture and without cue had the longest interpretation time (median: 48 s).
Localization cues increased inter-reader agreement and diagnostic confidence, reduced interpretation time in the detection of fractures on pediatric hand radiographs, while maintaining diagnostic accuracy.
比较有和没有定位提示的手部X线片检测儿童骨折的诊断准确性和解读时间。
纳入2019年至2021年连续2年以上因受伤接受X线检查且随访超过2周以确认是否存在骨折的儿童。4名对病史和诊断不知情的阅片者,在随机分组后至少间隔1周,对所有图像进行两次回顾,一次无提示,一次有提示,以确定是否存在骨折,若存在骨折,则记录解剖位置和诊断信心。记录每次检查的解读时间,并计算阅片者之间的平均值。使用Fleiss' kappa计算阅片者间一致性。采用敏感性、特异性和Mann-Whitney U相关性比较不同检查之间的诊断准确性和解读时间。
研究组包括92名有骨折的儿童(61名男孩,31名女孩;10.8±3.4岁)和40名无骨折的儿童(31名男孩,9名女孩;10.9±3.7岁)。提示提高了阅片者间一致性(κ从0.47提高到0.62)。虽然特异性降低(从63%降至62%),但敏感性(从75%提高到78%)、诊断准确性(从71%提高到73%)和信心提高(从78%提高到87%,p<0.01),且有定位提示检查的解读时间缩短(中位数:从40秒降至22秒,p<0.001)。具体而言,有骨折且有提示的检查解读时间最短(中位数:16秒),而无骨折且无提示的检查解读时间最长(中位数:48秒)。
定位提示提高了阅片者间一致性和诊断信心,缩短了儿童手部X线片骨折检测的解读时间,同时保持了诊断准确性。