Department of Thoracic Surgery, The Third Clinical College of Fujian Medical University, The First Hospital of Putian, No. 449 Nanmenxi Road, Putian, 351100, China.
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, No. 507 Zhengmin Road, Shanghai, 200433, China.
J Cardiothorac Surg. 2022 Aug 18;17(1):183. doi: 10.1186/s13019-022-01934-3.
To investigate feasibility and safety of autologous blood in preoperative computed tomography (CT)-guided localization of pulmonary ground-glass nodules (GGNs) by comparing to mico-coil prior to video-assisted thoracoscopic surgery.
Clinical data of patients with GGNs who underwent video-assisted thoracoscopic surgery followed by preoperative CT-guided autologous blood or micro-coil localization was retrospectively reviewed in our department between September 2019 and November 2021. The localization duration, localization success rate, localization-related complication, localization cost, operation time, and conversion rate were compared between the 2 localization groups.
Totally 65 patients with 65 GGNs were included in our study, with 34 patients in autologous blood group (group B) and 31 patients in micro-coil group (group M). There is no conversion to thoracotomy. The age, sex, nodule location, diameter of nodule and distance from the pleura between the 2 groups were statistically comparable. Compared with group M, group B had similar localization success rate (94.1% vs 83.9%, P = 0.183) but shorter localization time (14.50 ± 2.61 min vs 16.35 ± 2.30 min, P = 0.004), lower cost ($92.4 ± 3.2 vs $475.6 ± 8.5, P = 0.001), and lower incidence of puncture complications (3.0% vs 19.3%, P = 0.042).
The autologous blood localization is an effective and more economical method for preoperative GGNs localization, and is associated with fewer complications compared to micro-coil localization.
通过比较术前 CT 引导下经皮肺磨玻璃结节（GGN）自体血定位与微线圈定位，探讨在电视辅助胸腔镜手术（VATS）前进行自体血定位的可行性和安全性。
回顾性分析 2019 年 9 月至 2021 年 11 月我科 VATS 术前 CT 引导下经皮肺 GGN 行自体血或微线圈定位的患者的临床资料。比较两组患者的定位时间、定位成功率、定位相关并发症、定位费用、手术时间和中转开胸率。
共纳入 65 例 65 个 GGN 患者，其中 34 例接受自体血组（B 组），31 例接受微线圈组（M 组）。无中转开胸病例。两组患者的年龄、性别、结节位置、结节直径和距胸膜距离等差异均无统计学意义。与 M 组相比，B 组定位成功率相当（94.1% vs 83.9%，P = 0.183），但定位时间更短（14.50 ± 2.61 min vs 16.35 ± 2.30 min，P = 0.004），费用更低（92.4 ± 3.2 美元 vs 475.6 ± 8.5 美元，P = 0.001），穿刺并发症发生率更低（3.0% vs 19.3%，P = 0.042）。
与微线圈定位相比，术前 GGN 自体血定位是一种有效且经济的方法，并发症更少。
