Suppr超能文献

压力控制通气与不同容量控制通气模式之间的机械功率有所不同。

Mechanical Power Differs Between Pressure-Controlled Ventilation and Different Volume-Controlled Ventilation Modes.

作者信息

Rietveld Petra J, Snoep Jacob W M, Lamping Marjolein, van der Velde Franciska, de Jonge Evert, van Westerloo David W, Schoe Abraham

机构信息

All authors: Department of Intensive Care, Leiden University Medical Centre, Leiden, The Netherlands.

出版信息

Crit Care Explor. 2022 Aug 15;4(8):e0741. doi: 10.1097/CCE.0000000000000741. eCollection 2022 Aug.

Abstract

OBJECTIVES

Mechanical power (MP) is a way of estimating the energy delivered by the ventilator to the patient. For both volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) methods have been described to calculate the MP. The pressure-volume (PV) loop, from which the MP is calculated, is different for VCV compared with PCV. We aimed to compare the MP of VCV with zero pause time (VCV-0), VCV with 10% pause time (VCV-10), and PCV within patients in different patient categories based on severity of lung injury.

DESIGN

In a proof-of-concept study, we enrolled 46 mechanically ventilated patients without spontaneous breathing efforts. Baseline measurements were done in pressure-controlled mode. Subsequently, measurements were done in VCV-0 and VCV-10. Tidal volume and all other settings were kept the same.

SETTING

ICU, single university medical center.

PATIENTS

Fifty-eight cases in 46 patients on controlled ventilation modes.

INTERVENTIONS

Comparison between the MP of PCV, VCV-0, and VCV-10.

MEASUREMENT AND MAIN RESULTS

The mean MP of VCV-0, VCV-10, and PCV was 19.30, 21.80, and 20.87 J/min, respectively ( < 0.05 for all comparisons). The transpulmonary MP of VCV-0, VCV-10, and PCV was 6.75, 8.60, and 7.99 J/min, respectively ( < 0.05 for all comparisons).

CONCLUSIONS

In patients ventilated in a controlled mode, VCV without pause time had the lowest MP followed by PCV. VCV with 10% pause time had the highest MP.

摘要

目的

机械功率(MP)是估计呼吸机输送给患者能量的一种方式。对于容量控制通气(VCV)和压力控制通气(PCV),均已描述了计算MP的方法。计算MP所依据的压力-容积(PV)环,VCV与PCV有所不同。我们旨在比较零暂停时间的VCV(VCV-0)、暂停时间为10%的VCV(VCV-10)和PCV在不同肺损伤严重程度患者类别中的MP。

设计

在一项概念验证研究中,我们纳入了46例无自主呼吸努力的机械通气患者。在压力控制模式下进行基线测量。随后,在VCV-0和VCV-10模式下进行测量。潮气量和所有其他设置保持不变。

地点

重症监护病房,单一大学医学中心。

患者

46例接受控制通气模式的患者共58例。

干预措施

比较PCV、VCV-0和VCV-10的MP。

测量与主要结果

VCV-0、VCV-10和PCV的平均MP分别为19.30、21.80和20.87 J/分钟(所有比较均P<0.05)。VCV-0、VCV-10和PCV的跨肺MP分别为6.75、8.60和7.99 J/分钟(所有比较均P<0.05)。

结论

在接受控制模式通气的患者中,无暂停时间的VCV的MP最低,其次是PCV。暂停时间为10%的VCV的MP最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d7/9380695/ec7ff58629cd/cc9-4-e0741-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验