Ono T
Nihon Seikeigeka Gakkai Zasshi. 1987 Feb;61(2):205-15.
Subluxation of the hip and subsequent acetabular dysplasia were experimentally produced by fixing the knee of young rabbits in extension position. Changes of the acetabulum during the repair process after reduction were investigated radiologically, histologically and histomorphometrically. Radiologically, subluxation and acetabular dysplasia appeared two weeks after fixation and disappeared as the knee became flexible after removal of fixation. Histologically, abnormalities of growth cartilage and hypertrophy of trabeculae in the secondary spongiosa were prominent two weeks after fixation. Histomorphometrically, the bone area, osteoid surface and mineral appositional rate increased at this time. The above findings, however, were normalized as concentric reduction of the hip was achieved. Abnormal stress acting on the acetabulum caused hypertrophy of trabeculae, and this may result in the development of osteoarthritis. In order to prevent such a pathologic process, it is important to normalize the hip mechanically from the view point of bone dynamics.
通过将幼兔的膝关节固定于伸展位，实验性制造髋关节半脱位及继发的髋臼发育不良。复位后修复过程中髋臼的变化通过放射学、组织学及组织形态计量学方法进行研究。放射学检查显示，固定后两周出现半脱位及髋臼发育不良，去除固定膝关节恢复活动后上述表现消失。组织学检查显示，固定后两周生长软骨异常及次级骨松质内小梁肥大明显。组织形态计量学检查显示，此时骨面积、类骨质表面及矿物质沉积率增加。然而，随着髋关节实现同心复位，上述表现恢复正常。作用于髋臼的异常应力导致小梁肥大，这可能导致骨关节炎的发生。为防止这种病理过程，从骨动力学角度对髋关节进行力学矫正很重要。
