Moon Young-Seok, Cho Wan-Jae, Jung Youn-Sung, Lee Jun-Seok
Department of Orthopedic Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Orthopedic surgery, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Geriatr Orthop Surg Rehabil. 2022 Aug 10;13:21514593221119619. doi: 10.1177/21514593221119619. eCollection 2022.
Disseminated herpes zoster is defined as at least 20 skin lesions in multiple dermatomes. In particular, it has been reported mainly in patients with immunological defects. To our knowledge, there is no reported case of disseminated zoster in a non-immunocompromised patient with leg radiating pain and weakness.
A 74-year-old man visited our hospital with left leg radiating pain and left hip pain. He had no underlying disease other than hypertension. Neurologic examination revealed radiating pain on the L4 dermatome of the left leg. The muscle power was grade 3 for the hip flexor and knee extensor, and grade 4 for the ankle dorsiflexor and big toe dorsiflexor of the left leg. There were no sensory changes or skin lesions on his left leg. Herniation of the nucleus pulposus of the lumbar spine was suspected and lumbar magnetic resonance imaging (MRI) was performed. However, no pathologic lesions were seen on lumbar MRI. On the third day of hospitalization, erythematous patches and vesicles were observed on the head, face, ear, neck, trunk, back, and both lower extremities. Herpes zoster infection was confirmed by polymerase chain reaction analysis. Treatment was performed with 250 mg of intravenous acyclovir every 8 hours for 6 days and 62.5 mg of intravenous methylprednisolone for 4 days. On the 13th day of hospitalization, the skin lesions and left leg radiating pain and weakness improved.
We report the first case of disseminated herpes zoster involving the whole body in a non-immunocompromised patient complaining of left leg radiating pain and weakness. After treatment, both the patient's radiating pain and weakness improved.
播散性带状疱疹定义为多个皮节中至少有20个皮肤损害。特别是,它主要在免疫缺陷患者中报道。据我们所知,尚无关于非免疫功能低下且伴有腿部放射性疼痛和无力的患者发生播散性带状疱疹的报道。
一名74岁男性因左腿放射性疼痛和左髋疼痛前来我院就诊。除高血压外,他没有其他基础疾病。神经系统检查发现左腿L4皮节有放射性疼痛。左腿髋部屈肌和膝部伸肌肌力为3级,踝背屈肌和大足趾背屈肌肌力为4级。左腿无感觉改变或皮肤损害。怀疑有腰椎间盘突出症并进行了腰椎磁共振成像(MRI)检查。然而,腰椎MRI未发现病理性病变。住院第三天,在头部、面部、耳部、颈部、躯干、背部和双下肢观察到红斑和水疱。通过聚合酶链反应分析确诊为带状疱疹感染。治疗方案为每8小时静脉注射250mg阿昔洛韦,共6天,静脉注射62.5mg甲泼尼龙,共4天。住院第13天,皮肤损害以及左腿放射性疼痛和无力症状有所改善。
我们报告了首例在非免疫功能低下患者中发生的累及全身的播散性带状疱疹,该患者伴有左腿放射性疼痛和无力症状。治疗后,患者的放射性疼痛和无力症状均有所改善。