Mekheal Erinie, Kapoor Ashima, Roman Sherif, Mekheal Nader, Millet Christopher, Mekheal Marina, Maroules Michael
Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
Hematology and Oncology, St. Joseph's Regional Medical Center, Paterson, USA.
Cureus. 2022 Jul 15;14(7):e26901. doi: 10.7759/cureus.26901. eCollection 2022 Jul.
Pulmonary carcinosarcoma (PCS) is a rare type of non-small cell cancer. Overall, middle-aged and older smokers are the most affected age and sex groups. The diagnosis of PCS is difficult due to the absence of characteristic imaging findings. Additionally, preoperative biopsies do not usually reflect the heterologous nature of this tumor. Given the rarity of such tumors and the challenging diagnosis, the prognostic factors have not been established, and the overall prognosis remains poor. The valid therapeutic options are still limited. Here, we report a rare case of metastatic PCS that was accidentally discovered by imaging and properly diagnosed after surgical resection. The clinicopathological features, diagnostic tools, genetic theories, prognosis, and therapeutic options of this rare cancer are also discussed.
肺肉瘤样癌（PCS）是一种罕见的非小细胞癌。总体而言，中老年吸烟者是受影响最大的年龄和性别群体。由于缺乏特征性影像学表现，PCS的诊断较为困难。此外，术前活检通常不能反映该肿瘤的异质性。鉴于此类肿瘤的罕见性和诊断的挑战性，预后因素尚未明确，总体预后仍然较差。有效的治疗选择仍然有限。在此，我们报告一例罕见的转移性PCS病例，该病例通过影像学意外发现，并在手术切除后得到正确诊断。本文还讨论了这种罕见癌症的临床病理特征、诊断工具、遗传学理论、预后及治疗选择。
