比较手术切除、射频消融和 HIFU 治疗结直肠癌肝转移患者预后的网络荟萃分析方案。
Comparison of prognosis among patients with colorectal cancer liver metastases treated by surgical resection, radiofrequency ablation and HIFU: A protocol for network meta-analysis.
机构信息
Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Gansu, China.
Department of Peripheral Interventional Surgery, Affiliated Hospital of Gansu University of Traditional Chinese Medicine, Gansu, China.
出版信息
Medicine (Baltimore). 2022 Aug 19;101(33):e27915. doi: 10.1097/MD.0000000000027915.
BACKGROUND
Colorectal cancer is a malignant tumor second only to lung and breast cancer in the West. The liver is the main target organ for colorectal cancer metastasis, affecting the prognosis and survival. Surgical treatment has made great progress in colorectal cancer liver metastasis , including radiofrequency ablation (RFA), high-intensity focused ultrasound (HIFU) ablation.
OBJECT
Clinical treatments for colorectal cancer liver metastases are not the same. In order to clarify the impact of surgical resection, RFA and HIFU, we provided a decision-making basis for the clinical treatment of colon cancer liver metastasis through systematic reviews and network meta-analysis (NMA).
METHODS
We systematically searched the Chinese and English databases: PubMed, Embase, CENTRAL, CINAHL, Web of Science, CNKI, CBM, VIP, Wan Fang. Literature screening, data extraction, and quality evaluation were carried out by two researchers, and finally, use Stata to carry out meta-analysis.
RESULTS
This study is ongoing and the results will be submitted to a peer-reviewed journal for publication.
PROTOCOL REGISTRATION NUMBER
INPLASY202150044.
背景
结直肠癌是西方仅次于肺癌和乳腺癌的恶性肿瘤。肝脏是结直肠癌转移的主要靶器官，影响预后和生存。结直肠癌肝转移的外科治疗取得了很大进展，包括射频消融（RFA）、高强度聚焦超声（HIFU）消融。
目的
结直肠癌肝转移的临床治疗方法不尽相同。为了明确手术切除、RFA 和 HIFU 的影响，我们通过系统评价和网络荟萃分析（NMA）为结肠癌肝转移的临床治疗提供了决策依据。
方法
我们系统地检索了中英文数据库：PubMed、Embase、CENTRAL、CINAHL、Web of Science、CNKI、CBM、VIP、万方。由两名研究人员进行文献筛选、数据提取和质量评价，最终使用 Stata 进行荟萃分析。
结果
本研究正在进行中，结果将提交给同行评议期刊发表。
协议注册编号
INPLASY202150044。
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