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低度和中度近视患者不能进行角膜屈光手术时的最佳选择:后房有晶状体眼人工晶状体植入术。

The best choice for low and moderate myopia patients incapable for corneal refractive surgery: implantation of a posterior chamber phakic intraocular lens.

机构信息

Chongqing Aier Eye Hospital, Chongqing, 400020, China.

Aier Chongqing Optometry Eye hospital, No. 77, Daping Changjiang Second Road, Yuzhong, Chongqing, 400040, China.

出版信息

Int Ophthalmol. 2023 Feb;43(2):575-581. doi: 10.1007/s10792-022-02459-3. Epub 2022 Aug 19.

DOI:10.1007/s10792-022-02459-3
PMID:35984557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9971141/
Abstract

PURPOSE

This study aims to evaluate the early clinical outcomes of central hole phakic posterior chamber intraocular lens(ICLV4c) implantation for low and moderate myopia correction.

METHODS

This retrospective clinical study included 27 patients(47 eyes)who underwent ICLV4c implantation to correct myopia with spherical equivalent (SE) between - 1.75D and -6.0D. The uncorrected visual acuity (UCVA), intraocular pressure(IOP), central anterior chamber depth (ACD), vault, and endothelial cell density (ECD) were evaluated after surgery.

RESULTS

At one year follow-up, the postoperative UCVA of patients was higher than the preoperative CDVA and showed a stable trend. There was no significant difference in ECD (p > 0.05) one month after the surgery, the vault was 0.77 ± 0.32 mm, which decreased to 0.63 ± 0.26 mm after one year of surgery. Similarly, ACD was 3.24 ± 0.25 mm in the preoperative, which decreased significantly to 2.05 ± 0.39 mm at one month, while rose to 2.2 ± 0.39 mm at one year after surgery. There was no significant correlation between IOP and ACD and vault at one month and one year after surgery. The correlation coefficient between ACD and vault was found to be - 0.72 at one month after surgery, while the same -0.71 after one year. One patient developed visual fatigue, one with glare, and while no other complications were observed with the rest of the patients.

CONCLUSION

The ICL implantation is a safe, effective and stable method to correct low and moderate myopia, and may be a good alternative for patients with low and moderate myopia who cannot undergo corneal refractive surgery.

摘要

目的

本研究旨在评估中央孔有晶体眼后房型人工晶状体(ICLV4c)植入术矫正低度和中度近视的早期临床效果。

方法

本回顾性临床研究纳入了 27 名(47 只眼)接受 ICLV4c 植入术矫正近视屈光度在-1.75D 到-6.0D 之间的患者。术后评估裸眼视力(UCVA)、眼压(IOP)、中央前房深度(ACD)、拱高和内皮细胞密度(ECD)。

结果

术后 1 年随访时,患者术后 UCVA 高于术前最佳矫正视力(CDVA),且呈稳定趋势。术后 1 个月 ECD 无显著差异(p>0.05),拱高为 0.77±0.32mm,术后 1 年降至 0.63±0.26mm。同样,术前 ACD 为 3.24±0.25mm,术后 1 个月显著降至 2.05±0.39mm,术后 1 年升至 2.2±0.39mm。术后 1 个月和 1 年时,IOP 与 ACD 和拱高均无显著相关性。术后 1 个月和 1 年时,ACD 与拱高的相关系数分别为-0.72 和-0.71。1 例患者出现视觉疲劳,1 例出现眩光,其余患者均未出现其他并发症。

结论

ICLV4c 植入术是一种安全、有效、稳定的矫正低度和中度近视的方法,可能是不能接受角膜屈光手术的低度和中度近视患者的良好选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d1/9971141/672af9b675e9/10792_2022_2459_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d1/9971141/672af9b675e9/10792_2022_2459_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d1/9971141/672af9b675e9/10792_2022_2459_Fig1_HTML.jpg

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