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对3-甲基胆蒽诱导的淋巴瘤的遗传决定抗性在骨髓来源细胞水平上得以表达。

Genetically determined resistance to 3-methylcholanthrene-induced lymphoma is expressed at the level of bone marrow-derived cells.

作者信息

Ishizaka S T, Lilly F

出版信息

J Exp Med. 1987 Aug 1;166(2):565-70. doi: 10.1084/jem.166.2.565.

Abstract

Reciprocal bone marrow transfers were performed between mouse strains sensitive or resistant to 3-methylcholanthrene-induced thymic lymphoma. Sensitivity and resistance are properties inherent in bone marrow, and cannot be altered by maturation of marrow in an environment of the opposite phenotype.

摘要

在对3-甲基胆蒽诱导的胸腺淋巴瘤敏感或抗性的小鼠品系之间进行了相互骨髓移植。敏感性和抗性是骨髓固有的特性,并且不会因在相反表型的环境中骨髓成熟而改变。

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