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与职业性接触1,2 - 丙二醇二硝酸酯相关的心脏发病率和死亡率。

Cardiac morbidity and mortality associated with occupational exposure to 1,2 propylene glycol dinitrate.

作者信息

Forman S A, Helmkamp J C, Bone C M

出版信息

J Occup Med. 1987 May;29(5):445-50.

PMID:3598736
Abstract

Myocardial infarction and angina pectoris are conditions long associated with occupational exposure to nitroglycerin and related explosives. Cardiac sentinel events in selected munitions workers exposed to the related nitrated ester 1,2 propylene glycol dinitrate were identified and studied. Potentially exposed workers experienced significantly increased relative morbidity compared with control groups. There was no difference in hospitalizations for cardiac arrhythmias. The only cardiovascular mortality occurred in the control groups. The total number of cases was small. Possible sources of bias and causal speculations are discussed.

摘要

心肌梗死和心绞痛长期以来一直与职业性接触硝酸甘油及相关炸药有关。对选定的接触相关硝酸酯1,2 - 丙二醇二硝酸酯的弹药工人的心脏哨兵事件进行了识别和研究。与对照组相比,潜在暴露工人的相对发病率显著增加。心律失常的住院率没有差异。唯一的心血管死亡发生在对照组。病例总数较少。讨论了可能的偏倚来源和因果推测。

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