Méndez-Cruz Ana Rosa, Félix-Bermúdez Georgina Elizabeth, Aguilar-Escobar Dinora Virginia, Vega-Vega Lourdes, Morales-Estrada Aurea Itzel, Contreras-Rodríguez Araceli
Hospital Infantil Teletón de Oncología, Querétaro, Mexico.
Hospital Infantil Teletón de Oncología, Querétaro, Mexico.
Rev Argent Microbiol. 2023 Jan-Mar;55(1):68-72. doi: 10.1016/j.ram.2022.06.001. Epub 2022 Aug 18.
Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.
红球菌是一种已知可导致动物和人类感染的病原体，主要发生在免疫功能低下的患者中。本文描述了一例患有棒状红球菌引起的血流感染的儿科癌症患者。从血培养物中分离出革兰氏阳性杆菌。使用生化试验、基质辅助激光解吸电离飞行时间质谱技术和16S rRNA序列分析相结合的方法对目标细菌进行了鉴定。此外，使用E-test进行了药敏试验。分离出的细菌被鉴定为棒状红球菌。这名3岁患者成功接受了万古霉素和美罗培南治疗。这是首次发表的关于诊断为视网膜母细胞瘤并发生血流感染的儿科患者感染棒状红球菌的报告。在影响儿科癌症患者的机会性感染病原体中应考虑棒状红球菌。
