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基于脂质体纳米囊泡的超声技术在评估糖尿病女性异常妊娠结局中的应用。

Ultrasound Technique Based on Liposome Nanovesicles in the Evaluation of Abnormal Pregnancy Outcomes in Diabetic Women.

机构信息

Department of Ultrasound, Taiyuan Central Hospital, Taiyuan, 030009, China.

Department of Ultrasound, the Sixth Hospital of Shanxi Medical University, Taiyuan, 030000, China.

出版信息

Cell Mol Biol (Noisy-le-grand). 2022 Mar 31;68(3):383-389. doi: 10.14715/cmb/2022.68.3.42.

Abstract

Gestational diabetes mellitus (GDM) refers to the first occurrence or detection of glucose tolerance abnormalities during pregnancy, including cases that may have existed before pregnancy but have not been detected. It is one of the common complications during pregnancy. In recent years, the incidence of GDM is on the rise. The most common complication of GDM is macrosomia, which often causes dystocia, neonatal asphyxia, birth injury and postpartum bleached blood. Early diagnosis, appropriate treatment and maintenance of reasonable and stable blood glucose concentration can significantly reduce the incidence of complications. The purpose of this study was to investigate the application of ultrasound technique based on liposome nano-vesicles in the assessment of abnormal pregnancy outcomes in diabetic pregnant women. Objective: To investigate the value of ultrasound in the examination of fetal growth in pregnant women with gestational diabetes mellitus. Methods a total of 100 pregnant women with gestational diabetes admitted to the hospital were selected as the research objects, and the clinical data of ultrasound examination were retrospectively analyzed. According to the newborn weight, they were divided into control group (normal fetus group) and observation group (giant fetus group). The growth of fetuses in the two groups was compared, and the predictive value of each measurement index to the weight of giant fetus was analyzed.Multiple regression analysis showed that LL, AC and FL played a decisive role in fetal weight, with statistically significant differences (P<0.05). Conclusion Ultrasonography is of great value in predicting fetal growth in pregnant women with gestational diabetes mellitus and can be widely used.

摘要

妊娠期糖尿病(GDM)是指妊娠期首次发生或发现的葡萄糖耐量异常,包括可能在妊娠前已存在但未被检出的病例。它是妊娠期常见的并发症之一。近年来,GDM 的发病率呈上升趋势。GDM 最常见的并发症是巨大儿,常导致难产、新生儿窒息、产伤和产后大出血。早期诊断、适当治疗和维持合理、稳定的血糖浓度可显著降低并发症的发生率。本研究旨在探讨基于脂质体纳米囊泡的超声技术在评估糖尿病孕妇异常妊娠结局中的应用。目的:探讨超声检查在妊娠期糖尿病孕妇胎儿生长中的应用价值。方法:选取我院收治的 100 例妊娠期糖尿病孕妇为研究对象,回顾性分析其超声检查的临床资料。根据新生儿体重,将其分为对照组(正常胎儿组)和观察组(巨大儿组)。比较两组胎儿生长情况,并分析各测量指标对巨大儿体重的预测价值。多因素回归分析显示,LL、AC 和 FL 对胎儿体重起决定性作用,差异有统计学意义(P<0.05)。结论:超声检查对预测妊娠期糖尿病孕妇胎儿生长具有重要价值,可广泛应用。

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