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CircOMA1 promotes tumour growth and metastasis of bladder cancer by modulating IGF-IR/MAPK/EMT pathway.

作者信息

Zhang Lianghao, Zhan Yonghao, Li Longqing, Deng Haotian, Wang Jiange, Zhu Zhaowei, Zhang Xuepei

机构信息

Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. China.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, P. R. China.

出版信息

Clin Transl Med. 2022 Aug;12(8):e983. doi: 10.1002/ctm2.983.

DOI:10.1002/ctm2.983
PMID:35988263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9393076/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/ef6231bf35f5/CTM2-12-e983-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/6ac92c9c50e1/CTM2-12-e983-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/8b301e62747c/CTM2-12-e983-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/518dcd64a6e7/CTM2-12-e983-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/ef6231bf35f5/CTM2-12-e983-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/6ac92c9c50e1/CTM2-12-e983-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/8b301e62747c/CTM2-12-e983-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/518dcd64a6e7/CTM2-12-e983-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062d/9393076/ef6231bf35f5/CTM2-12-e983-g001.jpg

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本文引用的文献

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IGF‑IR promotes clonal cell proliferation in myelodysplastic syndromes via inhibition of the MAPK pathway.IGF-IR 通过抑制 MAPK 通路促进骨髓增生异常综合征中的克隆性细胞增殖。
Oncol Rep. 2020 Sep;44(3):1094-1104. doi: 10.3892/or.2020.7652. Epub 2020 Jun 19.
2
Comprehensive circular RNA profiling reveals the regulatory role of circ_100242/miR-145 pathway in bladder cancer.全面的环状RNA分析揭示了circ_100242/miR-145通路在膀胱癌中的调控作用。
Oncol Lett. 2020 Apr;19(4):2971-2978. doi: 10.3892/ol.2020.11380. Epub 2020 Feb 10.
3
Circular RNA, a novel marker for cancer determination (Review).
环状 RNA，癌症诊断的新型标志物（综述）。
Int J Mol Med. 2018 Oct;42(4):1786-1798. doi: 10.3892/ijmm.2018.3795. Epub 2018 Jul 30.
4
FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma.融合蛋白驱动 IGF-IR 信号的 FUS-DDIT3 在黏液样脂肪肉瘤中是一个治疗靶点。
Clin Cancer Res. 2017 Oct 15;23(20):6227-6238. doi: 10.1158/1078-0432.CCR-17-0130. Epub 2017 Jun 21.
5
IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights.胰岛素样生长因子-1受体（IGF-IR）信号传导在上皮-间质转化及IGF-IR靶向治疗中的作用：综述与新见解
Mol Cancer. 2017 Jan 30;16(1):6. doi: 10.1186/s12943-016-0576-5.
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Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis.环状RNA在外泌体中富集且稳定：一种有前景的癌症诊断生物标志物。
Cell Res. 2015 Aug;25(8):981-4. doi: 10.1038/cr.2015.82. Epub 2015 Jul 3.
7
Circular RNA: A new star of noncoding RNAs.环状 RNA：非编码 RNA 的新明星。
Cancer Lett. 2015 Sep 1;365(2):141-8. doi: 10.1016/j.canlet.2015.06.003. Epub 2015 Jun 5.
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9
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Ann Oncol. 2006 May;17 Suppl 5:v118-22. doi: 10.1093/annonc/mdj965.
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J Clin Oncol. 2000 Sep;18(17):3068-77. doi: 10.1200/JCO.2000.18.17.3068.