Department of Neurosurgery, Alzahra University Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Neurosurgery, Medical Image and Signal Processing Research Center, Alzahra University Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Mult Scler Relat Disord. 2022 Nov;67:104110. doi: 10.1016/j.msard.2022.104110. Epub 2022 Aug 13.
Multiple sclerosis (MS) can present with facial symptoms and signs, such as facial palsy, myokymia, and hemifacial spasm. Considering the importance of early diagnosis, treatment, and exclusion of causes other than MS, we aimed to assess the prevalence of these disorders in patients with MS.
MS patients who were referred to the Isfahan MS clinic from March 2021 to March 2022 were observed for facial presentations of the disease. A checklist of patients' baseline characteristics and disease features were then completed through patient interview and medical files.
Of the total of 2260 MS patients who were assessed, 3.27% had facial palsy, 1.28% had myokymia, and 0.84% presented with hemifacial spasm. The mean age of facial symptom onset was 30.74, 29.07, and 31.37 years, respectively. No relationship was found between the type of facial presentation and factors such as age, gender, subtype of MS, affected side of face, and time of presentation.
On the grounds that facial disorders can be the first presentation of MS, patients with atypical features of other common facial diseases such as Bell's palsy should therefore be carefully assessed and followed for any clues pertaining to the diagnosis of MS.
多发性硬化症（MS）可出现面部症状和体征，如面瘫、肌纤维颤动和半面痉挛。鉴于早期诊断、治疗和排除 MS 以外病因的重要性，我们旨在评估这些疾病在 MS 患者中的患病率。
对 2021 年 3 月至 2022 年 3 月期间被转诊到伊斯法罕 MS 诊所的 MS 患者进行观察，以评估其疾病的面部表现。然后通过患者访谈和病历完成患者基本情况和疾病特征检查表。
在评估的 2260 名 MS 患者中，3.27%有面瘫，1.28%有肌纤维颤动，0.84%有半面痉挛。面部症状出现的平均年龄分别为 30.74、29.07 和 31.37 岁。未发现面部表现类型与年龄、性别、MS 亚型、面部受累侧和出现时间等因素之间存在关系。
鉴于面部疾病可能是 MS 的首发表现，因此对于贝尔氏面瘫等其他常见面部疾病特征不典型的患者，应仔细评估并密切随访，以寻找与 MS 诊断相关的任何线索。
