School of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, People's Republic of China.
Department of Materials Science and Engineering, Shenzhen Key Laboratory of Interfacial Science and Engineering of Materials, Southern University of Science and Technology, Shenzhen 518055, People's Republic of China.
Carbohydr Polym. 2022 Nov 1;295:119852. doi: 10.1016/j.carbpol.2022.119852. Epub 2022 Jul 12.
This paper reports a versatile and dynamic hydrogel system based on ultrafast coordination between partially hydrogen-bonded (PHB) biopolymer hyaluronic acid and a series of transition metal ions at appropriate pH values. It was found that the procedure for the hydrogel synthesis was extremely facile, requiring a simple mixing of the components within 2 s. The hydrogels exhibited high water content, up to 96 %. Even so, the hydrogels can be stretched >50 times and rapidly self-heal from damage within only 10 s without using any healing agents or heating. Furthermore, this dynamic hydrogel network underwent reversible sol-gel transitions as response to multiple disparate stimuli, including pH, temperature, ions, redox, and light. The photo-patterning ability of the hydrogel with a rapid gel-sol transition upon exposure to light was also demonstrated. We disclosed the principle and methodology to use PHB metal-biopolymer systems for constructing dynamic bio-related soft matters.
本文报道了一种基于部分氢键化（PHB）生物聚合物透明质酸与一系列过渡金属离子在适当 pH 值下超快配位的多功能动态水凝胶体系。研究发现，水凝胶的合成过程非常简单，只需在 2 秒内简单混合各组分。该水凝胶具有高达 96%的高含水量，即使如此，水凝胶仍可拉伸超过 50 倍，并在不使用任何愈合剂或加热的情况下在 10 秒内迅速从损伤中自我修复。此外，这种动态水凝胶网络可作为对多种不同刺激（包括 pH 值、温度、离子、氧化还原和光）的响应进行可逆的溶胶-凝胶转变。水凝胶还表现出快速凝胶-溶胶转变的光图案化能力。我们揭示了使用 PHB 金属-生物聚合物系统构建动态生物相关软物质的原理和方法。
