澳大利亚啮齿动物南方伪鼠和亚历克西斯荒漠鼠生精上皮的细胞学组织

Cytological organization of the seminiferous epithelium in the Australian rodents Pseudomys australis and Notomys alexis.

作者信息

Peirce E J, Breed W G

出版信息

J Reprod Fertil. 1987 May;80(1):91-103. doi: 10.1530/jrf.0.0800091.

DOI:10.1530/jrf.0.0800091

Abstract

Absolute and relative testis mass of two species of conilurine rodents, the plains rat (Pseudomys australis) and the hopping mouse (Notomys alexis), were markedly different. In plains rats the testis comprised approximately 3% of body mass while in hopping mice they rarely accounted for more than 0.2%. In both species, 8 cellular associations, or cycle stages, were recognized in the seminiferous epithelium. The relative frequencies, and hence durations, of Stages I to VIII were 5.1, 7.0, 12.5, 10.5, 5.4, 25.9, 4.4 and 29.0% of one cycle for plains rats (N = 14), and 20.4, 10.9, 9.6, 8.1, 5.1, 20.4, 14.7 and 10.8% for laboratory-bred hopping mice (N = 35). Generally, the relative durations of the cycle stages were very similar between plains rat individuals, but were variable between hopping mice. Also, organization of the seminiferous epithelium was less rigid in hopping mouse testes, and several anomalies were observed. These included: the occurrence of 2-4 cellular associations in about 20% (range 11.3-33.9%) of tubular cross-sections, deviations in cellular composition in certain cycle stages from that usually observed, and an increased incidence of degenerating cells, together with the presence of multinucleated "giant' cells, within the seminiferous epithelium.

摘要

两种袋狸科啮齿动物，平原大鼠（Pseudomys australis）和跳鼠（Notomys alexis）的绝对和相对睾丸质量存在显著差异。平原大鼠的睾丸约占体重的3%，而跳鼠的睾丸很少超过体重的0.2%。在这两个物种中，生精上皮都识别出8种细胞组合或周期阶段。平原大鼠（N = 14）中，I至VIII期的相对频率以及相应的持续时间分别为一个周期的5.1%、7.0%、12.5%、10.5%、5.4%、25.9%、4.4%和29.0%；实验室饲养的跳鼠（N = 35）中则分别为20.4%、10.9%、9.6%、8.1%、5.1%、20.4%、14.7%和10.8%。一般来说，平原大鼠个体之间周期阶段的相对持续时间非常相似，但跳鼠之间则存在差异。此外，跳鼠睾丸中生精上皮的组织结构较不严格，观察到了一些异常情况。这些异常包括：在约20%（范围为11.3 - 33.9%）的管状横切面中出现2 - 4种细胞组合，某些周期阶段的细胞组成与通常观察到的情况存在偏差，生精上皮内退化细胞的发生率增加，以及多核“巨型”细胞的存在。