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一侧或两侧卵巢女性体外受精结果的比较

Comparison of in vitro fertilization results in women with one or two ovaries.

作者信息

Dodson M G, Young R L, Poindexter A N, Gibbons W E, Rossavik I K, Findley W E

出版信息

J Reprod Med. 1987 May;32(5):359-62.

PMID:3598984
Abstract

A study compared the in vitro fertilization results in women with one or two ovaries. Eighteen percent (23/125) of in vitro fertilization/embryo transfer cycles were in patients with one ovary. One-ovary patients averaged 4.2 follicles (greater than or equal to 10 mm) as compared to 7.9 in two-ovary patients, and significantly fewer ova were recovered from one-ovary patients (4.0 vs. 5.3). The total follicular volume was significantly less in one-ovary patients as compared to two-ovary patients, and the serum estradiol per follicle was less in one-ovary patients. However, the volume of the dominant follicle, the maximum serum estradiol levels, the number of ampules of Pergonal given and the ovum fertilization rate were not significantly different in one- and two-ovary patients. The mean number of embryos transferred was 3.9 +/- 1.9 in one-ovary patients and 4.5 +/- 1.8 in two-ovary patients (NS). Two pregnancies occurred in one-ovary patients (8.3% per laparoscopy) and 13 in two-ovary patients (12.9% per laparoscopy). The two one-ovary patients who achieved pregnancy behaved more like two-ovary patients in terms of peak serum estradiol levels and number of ova recovered.

摘要

一项研究比较了单卵巢和双卵巢女性的体外受精结果。18%(23/125)的体外受精/胚胎移植周期是在单卵巢患者中进行的。单卵巢患者平均有4.2个卵泡(大于或等于10毫米),而双卵巢患者为7.9个,单卵巢患者回收的卵子明显较少(4.0个对5.3个)。与双卵巢患者相比,单卵巢患者的卵泡总体积明显较小,且单卵巢患者每个卵泡的血清雌二醇含量较低。然而,单卵巢和双卵巢患者的优势卵泡体积、血清雌二醇最高水平、注射的 Pergonal 安瓿数量以及卵子受精率并无显著差异。单卵巢患者移植的胚胎平均数量为3.9±1.9个,双卵巢患者为4.5±1.8个(无显著差异)。单卵巢患者中有2例怀孕(每次腹腔镜检查的怀孕率为8.3%),双卵巢患者中有13例怀孕(每次腹腔镜检查的怀孕率为12.9%)。成功怀孕的2名单卵巢患者在血清雌二醇峰值水平和回收的卵子数量方面表现得更像双卵巢患者。

相似文献

1
Comparison of in vitro fertilization results in women with one or two ovaries.一侧或两侧卵巢女性体外受精结果的比较
J Reprod Med. 1987 May;32(5):359-62.
2
Evaluation of stimulated cycles with multiple follicular development but low oocyte retrieval.
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One ovary or two: differences in ovulation induction, estradiol levels, and follicular development in a program for in vitro fertilization.
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[Gonadotrophin dose and ovarian response: relations to the clinical outcome of in vitro fertilization and embryo transfer].[促性腺激素剂量与卵巢反应:与体外受精和胚胎移植临床结局的关系]
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Gonadotropin-releasing hormone antagonist and metformin for treatment of polycystic ovary syndrome patients undergoing in vitro fertilization-embryo transfer.促性腺激素释放激素拮抗剂与二甲双胍用于治疗接受体外受精-胚胎移植的多囊卵巢综合征患者。
Gynecol Endocrinol. 2006 May;22(5):235-8. doi: 10.1080/14767050600761893.

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Biological Impact of Unilateral Oophorectomy: Does the Number of Ovaries Really Matter?单侧卵巢切除术的生物学影响:卵巢数量真的重要吗?
Geburtshilfe Frauenheilkd. 2021 Mar;81(3):331-338. doi: 10.1055/a-1239-3958. Epub 2020 Oct 1.