刺激频率对经颅诱发电位的影响。
The effect of stimulation frequency on transcranial evoked potentials.
作者信息
Leodori Giorgio, Rocchi Lorenzo, Mancuso Marco, De Bartolo Maria Ilenia, Baione Viola, Costanzo Matteo, Belvisi Daniele, Conte Antonella, Defazio Giovanni, Berardelli Alfredo
机构信息
IRCCS Neuromed, 86077 Pozzilli (IS), Italy.
Department of Human Neurosciences, Sapienza University of Rome, 00185 Rome (RM), Italy.
出版信息
Transl Neurosci. 2022 Aug 5;13(1):211-217. doi: 10.1515/tnsci-2022-0235. eCollection 2022 Jan 1.
INTRODUCTION
Transcranial magnetic stimulation-evoked electroencephalography potentials (TEPs) have been used to study motor cortical excitability in healthy subjects and several neurological conditions. However, optimal recording parameters for TEPs are still debated. Stimulation rates could affect TEP amplitude due to plasticity effects, thus confounding the assessment of cortical excitability. We tested whether short interpulse intervals (IPIs) affect TEP amplitude.
METHODS
We investigated possible changes in TEP amplitude and global mean field amplitude (GMFA) obtained with stimulation of the primary motor cortex at IPIs of 1.1-1.4 s in a group of healthy subjects.
RESULTS
We found no differences in TEP amplitude or GMFA between the first, second and last third of trials.
DISCUSSION
Short IPIs do not affect TEP size and can be used without the risk of confounding effects due to short-term plasticity.
引言
经颅磁刺激诱发脑电图电位（TEP）已被用于研究健康受试者及多种神经系统疾病中的运动皮质兴奋性。然而，TEP的最佳记录参数仍存在争议。由于可塑性效应，刺激频率可能会影响TEP振幅，从而混淆对皮质兴奋性的评估。我们测试了短脉冲间隔（IPI）是否会影响TEP振幅。
方法
我们在一组健康受试者中，研究了以1.1 - 1.4秒的IPI刺激初级运动皮质时，TEP振幅和全局平均场振幅（GMFA）可能发生的变化。
结果
我们发现在试验的前三分之一、中间三分之一和后三分之一中，TEP振幅或GMFA没有差异。
讨论
短IPI不会影响TEP大小，并且可以使用，而不会因短期可塑性产生混淆效应的风险。
Zotero 插件