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Scanning acoustic microscopy visualizes cytomechanical responses to cytochalasin D.

作者信息

Bereiter-Hahn J

出版信息

J Microsc. 1987 Apr;146(Pt 1):29-39. doi: 10.1111/j.1365-2818.1987.tb01324.x.

DOI:10.1111/j.1365-2818.1987.tb01324.x
PMID:3599068
Abstract

The reactions of XTH-2 cells (line derived from Xenopus laevis tadpole hearts) to cytochalasin D (CD) were followed using scanning acoustic microscopy (SAM) at 0.9 GHz, fluorescence and electron microscopy. The first reaction to CD which can be detected by SAM is a loss of image contrast, indicating a decrease in acoustic impedance of about 30%. Based on structural changes revealed by staining of actin with TRITC-phalloidin, and taking theoretical considerations into account, a relationship between impedance decrease and tension in the actin fibrillar system is deduced.

摘要

相似文献

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Scanning acoustic microscopy visualizes cytomechanical responses to cytochalasin D.
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引用本文的文献

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Acoustic microscopy of cultured cells. Distribution of forces and cytoskeletal elements.培养细胞的声学显微镜检查。力和细胞骨架成分的分布。
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